Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E
Abosedera, D., Abd Elfatah, E., Tammam, O., Badr, O., Refaey, M. (2022). Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E. EKB Journal Management System, 1(1), 145-155. doi: 10.21608/ijesr.2022.288686
Dalia Abosedera; Emara Abd Elfatah; Omar Tammam; Osama Badr; Mohamed Refaey. "Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E". EKB Journal Management System, 1, 1, 2022, 145-155. doi: 10.21608/ijesr.2022.288686
Abosedera, D., Abd Elfatah, E., Tammam, O., Badr, O., Refaey, M. (2022). 'Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E', EKB Journal Management System, 1(1), pp. 145-155. doi: 10.21608/ijesr.2022.288686
Abosedera, D., Abd Elfatah, E., Tammam, O., Badr, O., Refaey, M. Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E. EKB Journal Management System, 2022; 1(1): 145-155. doi: 10.21608/ijesr.2022.288686

Effect of Asphodelus Microcarpus on Low Pathogenic Coronavirus 229E

International Journal of Environmental Studies and Researches
Article 13, Volume 1, Issue 1, June 2022, Page 145-155  XML PDF (344.12 K)
Document Type: Original scientific articles
DOI: 10.21608/ijesr.2022.288686
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Authors
Dalia Abosedera1; Emara Abd Elfatah2; Omar Tammam* 1; Osama Badr3; Mohamed Refaey3
1Environmental Studies and Research Institute, University of Sadat City
2Biotechnology Institute (GEBRI), University of Sadat City, Sadat City
3Faculty of Pharmacy, University of Sadat City, Menoufia
Abstract
Abstract
Human coronavirus and several picornaviruses are responsible for worldwide epidemic outbreaks, thus representing a heavy burden to their hosts. Coronaviruses (CoVs), enveloped positive-sense RNA viruses, are characterized by club-like spikes that project from their surface, an unusually large RNA genome, and a unique replication strategy. Roots of Asphodelus microcarpus- which planted in Marsa Matroh Governorate El-Dabaa region is the main food of Spalax leucodon Egyptiacus which showed immunity to many diseases. This plant was  mainly reported to have anthraquinone and its derivatives. Asphodelus microcarpus tuber was extracted using methanol 80% that can extract polar, semi-polar, and non-polar compounds. Subsequently the methanolic extract was fractionated to, ethyl acetate. The present work showed that significant antiviral activity of A.microcarpus against coronavirus 229E, further studies  are required to  emphasizes this effect.
 
Keywords
Keywords: Asphodelus microcarpus; Coronavirus 229E; Cytotoxicity; Spalax leucodon Egyptiacus
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