ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS
Elkassar, Y., gaafar, S., ElSabaa, B., Mohamed, D. (2023). ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS. EKB Journal Management System, 5(1), 36-37. doi: 10.21608/alexpo.2023.197468.1576
Yasser Elkassar; sherif gaafar; Basma Mohamed ElSabaa; Dina Ahmed Hassan Mohamed. "ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS". EKB Journal Management System, 5, 1, 2023, 36-37. doi: 10.21608/alexpo.2023.197468.1576
Elkassar, Y., gaafar, S., ElSabaa, B., Mohamed, D. (2023). 'ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS', EKB Journal Management System, 5(1), pp. 36-37. doi: 10.21608/alexpo.2023.197468.1576
Elkassar, Y., gaafar, S., ElSabaa, B., Mohamed, D. ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS. EKB Journal Management System, 2023; 5(1): 36-37. doi: 10.21608/alexpo.2023.197468.1576

ASSOCIATION BETWEEN CHRONIC ENDOMETRITIS AND UNEXPLAINED RECURRENT PREGNANCY LOSS

ALEXMED ePosters
Article 1, Volume 5, Issue 1, January 2023, Page 36-37  XML
Document Type: Preliminary preprint short reports of original research
DOI: 10.21608/alexpo.2023.197468.1576
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Authors
Yasser Elkassar1; sherif gaafar2; Basma Mohamed ElSabaa3; Dina Ahmed Hassan Mohamed email 4
1Alexandria university obstetric&gynecology
2ob/gyn, faculty of medicine, alexandria university
3Department of Pathology, Faculty of Medicine, Alexandria University
4Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria University
Abstract
Pregnancy loss is defined as the spontaneous end of a pregnancy before the fetus has reached viability and encompasses all losses from conception until 20–24 weeks gestation.(1) Recurrent pregnancy loss (RPL) is the failure of two or more clinically recognized pregnancies.(1, 2)
Chronic endometritis (CE) is defined as localized inflammation of the endometrial mucosa characterized by the presence of edema, increased stromal cell density, dissociated maturation between epithelial cells and stroma fibroblasts, as well as the presence of plasma cell infiltrate in the stroma. (3)
The reported prevalence in CE women with RPL ranges from 9% to 56%. Update, the impact of CE on reproductive capacity is controversial, but reports suggest it may negatively affect fertility outcomes.(4)
AIM OF THE WORK:
The study aimed to assess the association between chronic endometritis and unexplained recurrent pregnancy loss.
PATIENTS AND METHODS:
A case series study was conducted at El-Shatby University Maternity Hospital on 30 women aged less than 35 years with unexplained RPL.
Informed consent was obtained from all patients who were included in the study, and they were subjected to complete history taking, laboratory investigations, and transvaginal Ultrasound.
The office hysteroscopy procedures were scheduled in the follicular phase of the menstrual cycle (Day 3–15). At the end of each procedure, an endometrial biopsy was obtained. The endometrial biopsies were examined by routine Hematoxylin and Eosin (H & E) stain. Finally, immunohistochemical staining for the plasma cell marker CD138 was performed.
Keywords
ASSOCIATION; ENDOMETRITIS; RECURRENT PREGNANCY LOSS
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