Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals
Abdel Baseer, K., Mohammed, A., Esmail, Y., Qubaisi, H. (2023). Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals. EKB Journal Management System, 6(1), 561-570. doi: 10.21608/svuijm.2022.156560.1381
Khaled A. Abdel Baseer; Abdallah E. Mohammed; Yasmine Muhammed Esmail; Heba M. Qubaisi. "Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals". EKB Journal Management System, 6, 1, 2023, 561-570. doi: 10.21608/svuijm.2022.156560.1381
Abdel Baseer, K., Mohammed, A., Esmail, Y., Qubaisi, H. (2023). 'Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals', EKB Journal Management System, 6(1), pp. 561-570. doi: 10.21608/svuijm.2022.156560.1381
Abdel Baseer, K., Mohammed, A., Esmail, Y., Qubaisi, H. Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals. EKB Journal Management System, 2023; 6(1): 561-570. doi: 10.21608/svuijm.2022.156560.1381

Relation between vitamin D deficiency and recurrent acute diarrhea in children under the age of five years in Qena university hospitals

SVU-International Journal of Medical Sciences
Article 55, Volume 6, Issue 1, January 2023, Page 561-570  XML PDF (192.26 K)
Document Type: Original research articles
DOI: 10.21608/svuijm.2022.156560.1381
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Authors
Khaled A. Abdel Baseer1; Abdallah E. Mohammed2; Yasmine Muhammed Esmail email 1; Heba M. Qubaisi1
1Department of Pediatrics, Faculty of Medicine, South Valley University, Qena, Egypt
2Department of Clinical Pathology , Faculty of Medicine, South Valley University, Qena, Egypt
Abstract
Background: Worldwide, children have a very high prevalence of vitamin D deficiency. Epidemiological evidence connects vitamin D deficiency to immune system dysfunction and an elevated risk of infections. For the therapy of acute diarrhea in children, it may be useful to know how vitamin D deficiency affects the severity of the condition.
Objectives: To study the relation between vitamin D deficiency and recurrent acute diarrhea in children.
Patients and Methods: A Hundred Egyptian children (1 month to 5 years old) with a history of recurrent attacks of acute diarrhea were enrolled in the study. They were subjected to complete history, clinical examination and laboratory investigation including vitamin D assays.
 Results: we found a positive correlation between vitamin D deficiency and recurrent acute diarrhea. Vitamin D deficiency was deficient in 15%, insufficient in 17%, and sufficient in 68% of children with recurrent acute diarrhea. There was a significantly decreased percentage of vitamin D supplementation in deficient patients (20%) when compared with insufficient patients (64.7%) and sufficient patients (63.2%). There was a highly significantly increased total number of diarrhea episodes in deficient patients (5.6 ± 1.1) when compared with insufficient patients (4.3 ± 1.5) and sufficient patients (2.2 ± 0.9).
Conclusion: This study pays attention to the role of vitamin D in the susceptibility to infection-related illness in children.
Keywords
Vitamin D; Recurrent Acute Diarrhea; Children
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