Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy
Abdalla, T., Abdelmoktader, A., Saad, M. (2023). Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy. EKB Journal Management System, 90(2), 3312-3322. doi: 10.21608/ejhm.2023.291348
Tarek Rashad Abdalla; Ahmed Mahmoud Abdelmoktader; Mohamed Ahmed Saad. "Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy". EKB Journal Management System, 90, 2, 2023, 3312-3322. doi: 10.21608/ejhm.2023.291348
Abdalla, T., Abdelmoktader, A., Saad, M. (2023). 'Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy', EKB Journal Management System, 90(2), pp. 3312-3322. doi: 10.21608/ejhm.2023.291348
Abdalla, T., Abdelmoktader, A., Saad, M. Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy. EKB Journal Management System, 2023; 90(2): 3312-3322. doi: 10.21608/ejhm.2023.291348

Cranial Ultrasound and Serum Amyloid A as Predictors of Outcome in Term Newborn with Hypoxic-Ischemic Encephalopathy

The Egyptian Journal of Hospital Medicine
Article 202, Volume 90, Issue 2, January 2023, Page 3312-3322  XML PDF (781.27 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2023.291348
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Authors
Tarek Rashad Abdalla email ; Ahmed Mahmoud Abdelmoktader; Mohamed Ahmed Saad
Abstract
Background: The use of serum amyloid A as a synergistic predictor of the level and extent of brain injury has been mentioned by many literatures yet no correlation between resistive index -as a reflector of cerebral blood flow velocity- cranial imaging and mortality outcomes have been detected.
Objectives:This study aimed to evaluate serum amyloid A and cranial ultrasound (CUS) in hypoxic ischemic insult and assess its relation to consequences as mortality in neonates.
Subjects and Methods: A prospective cohort study was done on 35 full term (>35 weeks) neonates in Intensive Care Unit-Fayoum Hospital - Egypt. Full neurological examination was done during the first 24 hours and after 7 days.
Results: Severe hypoxic ischemia was found strongly correlated with high mortality. Low resistive index and high serum amyloid A were both indicators of poor prognostic condition in asphyxiated neonates.
Conclusion: The serum amyloid A and ultrasound can be involved to evaluate the extent and level of asphyxia in neonates upon the first days of life.
 
Keywords
Hypoxic ischemia; Encephalopathy; Resistive index; Serum amyloid A
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