The Use of Negative Pressure Wound Therapy in Infected Burn Wounds: Bridging the Gap | ||||
The Egyptian Journal of Plastic and Reconstructive Surgery | ||||
Article 3, Volume 47, Issue 2, April 2023, Page 89-95 PDF (8.29 MB) | ||||
Document Type: Research article | ||||
DOI: 10.21608/ejprs.2023.291376 | ||||
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Authors | ||||
Ahmed Nawar ![]() | ||||
The Department of Plastic Surgery, Faculty of Medicine, Cairo University | ||||
Abstract | ||||
Background: Burns represent one of the most devastating modes of trauma with significant morbidity and mortality. Despite advances in burns care, infection remains one of the leading causes of death. Burn excision is mandatory in infected cases and need to be temporarily covered with allografts, however this is not available in many settings. Negative pressure wound therapy (NPWT) has become an integral part of wound management, and is being used in burns with different indications. Objective: The use of NPWT as a temporary coverage after excision of infected burns for wound bed preparation before autografting, and to compare the outcomes with those of early excision and grafting. Patients and Methods: Ten patients with 15 burn wounds were allocated to 2 groups; group A patients presented late with infected burns while group B presented early. Group A had excision followed by NPWT and autografting when ready, and Group B had early excision and grafting. Both groups' outcomes were compared in terms of wound size, graft take and laboratory markers. Results: Both groups included different mechanisms of burns, various age groups, total burn surface area (TBSA) up < br />to 30%. Most Group A patients had a reduction of wound size (mean 5.1%) with using NPWT, and the average graft take was 83.9% and 85% for Group A and Group B respectively. Inflammatory markers were reduced in Group A patients, who also showed an increase in serum albumin compared to Group B. Conclusions: NPWT should be considered for temporary coverage after excision of infected burns before autografting. It may minimize the size of the wound, and can increase graft take that can be comparable to cases excised and grafted early. Further work is needed to assess NPWT against allografts in infected burns, and to investigate its use with early excision. | ||||
Keywords | ||||
Negative Pressure; Burns; Infection; Grafts | ||||
References | ||||
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