Clinical Features of COVID-19 Hospitalized Patients with different degree of Proteinuria | ||||
| Zagazig University Medical Journal | ||||
| Article 31, Volume 30, Issue 3, May and June 2024, Page 889-896 PDF (869.59 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2023.199528.2767 | ||||
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| Authors | ||||
Ahmed Noaman1; Yaser A Elhendy2; Sameh Hussein Abdel-Hamid 3; Mahmoud Nabil Kamel  3; Usama Ragab 1
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| 1Internal Medicine Department, Faculty of Medicine, Zagazig University, Egypt | ||||
| 2Internal medicine, faculty of medicine zagazig University zagazig Egypt | ||||
| 3Al-Ahrar Teaching Hospital, Zagazig, Egypt. | ||||
| Abstract | ||||
| Background: Coronavirus disease-19 (COVID-19) is a lung disease that also negatively affects several organ systems. Patients with COVID-19 frequently have kidney dysfunction. The exact impact of proteinuria and its degree on the clinical outcome of patients with COVID-19 is unclear. Objective: This study aimed to assess the effect of different degrees of proteinuria on the clinical outcome of hospitalized patients with COVID-19. Patients and methods: This study included 100 patients with COVID-19 at Isolation Department, Zagazig University and Al-Ahrar Teaching Hospitals who presented with proteinuria on admission. Patients were divided into two groups based on their urine protein creatinine ratio (UPCR): those with UPCR less than 1gm and those with UPCR greater than 1gm. Results: There is a statistically significant relation between the two groups regarding neutrophil count (p=0.027) (higher in patients with UPCR > 1gm), and lymphocytes (p=0.003) (lower in patients with UPCR > 1gm). There is a statically significant relation between the degree of proteinuria and the incidence of acute kidney injury (p<0.001) (proteinuria higher in those who developed AKI). Also, there is a significant difference between the two groups regarding the conscious level (p=0.019) (disturbed conscious level more in patients with UPCR >1gm). Conclusion: Proteinuria in COVID-19 hospitalized patients is associated with poor clinical outcomes and could lead to further renal deterioration and AKI, so it is important to screen for it. | ||||
| Keywords | ||||
| COVID 19; Proteinuria; Acute kidney injury; Clinical Outcome | ||||
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