Formulated Posterior Subtenon Triamcinolone Versus Triamcinolone Alone in The Management of Macular Edema Secondary to Non-Ischemic Retinal Vein Occlusions | ||||
| International Journal of Medical Arts | ||||
| Article 2, Volume 5, Issue 1, January 2023, Page 2938-2943 PDF (889.19 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ijma.2023.191761.1616 | ||||
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| Author | ||||
Ehab Tharwat  
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| Department of Ophthalmology, Damietta Faculty of Medicine, Al-Azhar University, Damietta, Egypt | ||||
| Abstract | ||||
| Background: Visual impairment, and even blindness, can result from Retinal Vein Occlusion [RVO], making it the second most common vascular disorder of the retina after diabetic retinopathy. Aim of the Work: To evaluate the effectiveness of the posterior subtenon triamcinolone acetonide [PSTA] alone or formulated in the treatment of macular edema caused by central or branch non-ischemic retinal vein occlusions. Patients and Methods: Our study included 78 patients, divided into two groups; Formulated PSTA group and PSTA alone group, each of them 39 patients. The NAGATA subtenon cannula was used to administer 40 mg of triamcinolone acetonide [TA] to both groups via the posterior subtenon channel. Results: At one month, the BCVA improved from 0.4 [0.1 - 0.71] at the baseline to 0.80 [0.10-1.00] in the formulated group, unlike PSTA alone group which was no improvement. This was associated with a reduction in the CMT in the formulated group more than in the PSTA alone group. In the third month, the BCVA increased to 0.90 [0.20-1.00] in formulated group and remain constant in the sixth month. However, in PSTA alone group, the improvement in the BCVA started occurring in the third month which increases from 0.40 [0.10-0.90] at the baseline and the first month to 0.60 [0.20-1.00] in the third month and 0.80 [0.20-1.00] at sixth month. No elevation in the IOP in both groups. Conclusion: We found that formulated TA is more efficacious than TA alone in improving BCVA and lowering CMT in patients with ME related to Non-Ischemic RVO when administered early in the disease process, without causing any elevation in intraocular pressure. | ||||
| Keywords | ||||
| Formulated PSTA; Retinal vein occlusion; Subtenon; Triamcinolone; Macular edema | ||||
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