Preparation and Evaluation of Combined Polyvalent Inactivated Vaccine for The Protection Against Chronic Respiratory Disease in Chickens | ||||
| Zagazig Veterinary Journal | ||||
| Article 19, Volume 43, Issue 1, March 2015, Page 182-190 PDF (637.72 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zvjz.2015.29367 | ||||
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| Authors | ||||
| Fatma M Gadallah1; Salama S S1; F R El-Seedy2 | ||||
| 1Central Laboratory for Evaluation of Veterinary Biologics (CLEVB), Abbasia – Cairo. | ||||
| 2Dept, of Microbiology, Faculty of Veterinary Medicine, Beni Suif University. | ||||
| Abstract | ||||
| Chronic respiratory disease (CRD) is one of the major problems within the poultry farms. In this study, a polyvalent inactivated M. gallisepticum and Escherichia coli vaccine was prepared then evaluated using both serological and vaccination challenge tests. Results of this vaccine was promising, where the peak of humoral immune response against M. gallisepticum as measured by ELISA were 2418 and 5600 when taken in either single or booster doses respectively while were 2240 and 3576 for E. coli. As regards to the protection against challenge with virulent bacterial strains, the achieved protection percentages against M. gallisepticum virulent strain were 62 and 72 post single and booster doses while were 66.67 and 77.47 for E. coli. The achieved results could help to be concluded that the locally prepared polyvalent M. gallisepticum and E. coli vaccine may help and minimize the problem of the chronic respiratory diseases in poultry farms. | ||||
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