Evaluation of Locally Prepared Inactivated Newcastle Disease Virus Vaccine | ||||
| Benha Veterinary Medical Journal | ||||
| Article 26, Volume 34, Issue 2, June 2018, Page 278-290 PDF (496.54 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bvmj.2018.29438 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Nermin M. Monir1; Lamia M. Omar1; Gabr F. El-Bagoury2; Saad S. A. Sharawi2 | ||||
| 1Central Laboratory for Evaluation of Veterinary Biologics, Cairo | ||||
| 2Department of virology, Faculty of Veterinary Medicine, Benha University | ||||
| Abstract | ||||
| Vaccination is one of the control measures of the disturbing Newcastle Disease in Egypt. Inactivated Newcastle Disease virus (NDV) vaccine was prepared using a local isolate (NDV-ch-EG-CLEVBF604- 2016), from Qaliobia governorate, Egypt, with Montanide ISA70VG as an oil adjuvant. The prepared vaccine was evaluated in comparison with an inactivated imported vaccine. Chick and Turkey chick groups vaccinated with either prepared or imported vaccines showed high serum antibody titers from the 3rd week post vaccination and reached the highest titer at the 9th week post vaccination using HI test. Both prepared and imported vaccines gave near percentage of protection against the local and the classical strain in both groups of chicks and turkeys ,21 days post vaccination, with no clinical signs or lesions on examination. Concluding that the locally prepared inactivated NDV vaccine can protect chicken and turkey against both homologous and heterologous challenging viruses. | ||||
| Keywords | ||||
| ND; Evaluation; inactivated vaccine; Montanide ISA70VG | ||||
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