Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient
Baheir, S., Attia, M., Dawaba, A. (2023). Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient. EKB Journal Management System, 10(1), 401-411. doi: 10.21608/adjg.2023.103233.1429
Salma M. Baheir; Mai S. Attia; Aya M. Dawaba. "Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient". EKB Journal Management System, 10, 1, 2023, 401-411. doi: 10.21608/adjg.2023.103233.1429
Baheir, S., Attia, M., Dawaba, A. (2023). 'Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient', EKB Journal Management System, 10(1), pp. 401-411. doi: 10.21608/adjg.2023.103233.1429
Baheir, S., Attia, M., Dawaba, A. Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient. EKB Journal Management System, 2023; 10(1): 401-411. doi: 10.21608/adjg.2023.103233.1429

Evaluation of Controlled Release Simvastatin around Dental Implant in Controlled Type II Diabetic Patient

Al-Azhar Dental Journal for Girls
Article 7, Volume 10, Issue 1, January 2023, Page 401-411  XML PDF (612.12 K)
Document Type: Original Article
DOI: 10.21608/adjg.2023.103233.1429
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Authors
Salma M. Baheir email 1; Mai S. Attia2; Aya M. Dawaba3
1Dentist at Medical Administration Center, Al-Azhar University, Cairo, Egypt
2Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology, Faculty of Dental Medicine for Girls Al-Azhar University & Faculty of Oral and Dental Medicine, Misr International University, Cairo, Egypt
3Associate Professor of Pharmaceutics, Faculty of Pharmacy Al-Azhar University, Cairo, Egypt
Abstract
Purpose: The goal of this study was to evaluate the clinical effect of topically controlled release simvastatin with dental implant in type II diabetic patients. Materials and Methods: Sixteen diabetic type II patients with missing teeth were selected according to inclusion and exclusion criteria. Patients were divided randomly into two groups using flip coin method. Group I (test group): 8 patients underwent implant placement for missed tooth with controlled released simvastatin around the implant. Group II (control Group): 8 patients underwent implant placement for missed tooth without controlled released simvastatin around the implant. All patients were followed up clinically and radio-graphically for 6 months postoperatively after implant placement. Results: The use of Simvastatin controlled release gel with delayed dental implants decrease postoperative pain and swelling Conclusion: This research showed that the drug delivery system of controlled release simvastatin improve the repair and healing of bone and soft tissue around dental implant in diabetic type II patients
Keywords
Dental implant; Diabetes type II; Simvastatin
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