Impact of diabetes mellitus on acute and short term left ventricular longitudinal systolic strain recovery after percutaneous coronary intervention in ischemic hypertensive patients | ||||
| SVU-International Journal of Medical Sciences | ||||
| Article 13, Volume 6, Issue 2, July 2023, Page 152-159 PDF (353.55 K) | ||||
| Document Type: Original research articles | ||||
| DOI: 10.21608/svuijm.2023.202042.1556 | ||||
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| Authors | ||||
Areej Alkhateeb1; Nihal Salah Abd Elrady  1; Ahlam Mohammed Sabrah Ali2; Abdel Kader Ahmed Hashim 3
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| 1Cardiology Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| 2G.I.T Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| 3Nephrology Unit, Internal Medicine department, Faculty of Medicine, South Valley University, Qena, Egypt | ||||
| Abstract | ||||
| Background: Diabetes mellitus (DM) is linked to an increased risk of cardiovascular disease and almost one-third of patients with acute myocardial infarction (AMI) may have undetected diabetes mellitus (DM) at the time of admission. Objectives: evaluate the impact of DM on the subtle changes in left ventricular (LV) function before and post revascularization in ischemic hypertensive patients. Patients and Methods: This was an observational prospective study performed at Qena University Hospital included 140 ischemic hypertensive patients . Patients were divided into two groups: (1) Diabetic group and (2) non diabetic group. A complete medical history, physical examination and laboratory tests were done as well as Trans thoracic Echocardiography (TTE) was done before and after PCI for each patient. Results: In this study, there was a statistically significant (p-value < 0.05) increase in LV GLS after PCI (-14.0 ± 3.6%) when compared with GLS before PCI (-13.7 ± 1.5%) in diabetic group and highly statistically significant(p-value < 0.001) increased GLS after PCI (-15.8 ± 1.1%) when compared with GLS before PCI (-14.2 ± 0.9%) in non-diabetic group. Also we found that after PCI, diabetic patients had a significant improvement in LV EF and dimensions than the non-diabetic group that resulted in highly significant increase in GLS. Conclusion: The presence of diabetes mellitus in ischemic hypertensive patients had an impact on subclinical LV function that has been improved after successful revascularization regardless the level of HbA1C. | ||||
| Keywords | ||||
| Acute coronary syndromes (ACS; Ischemic heart disease (IHD); percutaneous coronary intervention (PCI); Global longitudinal strain (GLS); Left ventricle (LV) | ||||
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