Cryptococcus laurentii fungaemia in a Tertiary Hospital in Nigeria: Case reports | ||||
| Microbes and Infectious Diseases | ||||
| Article 39, Volume 4, Issue 4, November 2023, Page 1428-1434 PDF (717.84 K) | ||||
| Document Type: Short Reports (case reports) | ||||
| DOI: 10.21608/mid.2023.182374.1429 | ||||
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| Authors | ||||
Adeyinka Afolake Davies   1; Chioma Osuagwu2; Victoria Aikhomu2; Rita O. O. Oladele2
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| 1Department of Medical Microbiology, Olabisi Onabanjo University Teaching Hospital | ||||
| 2Department of Medical Microbiology and Parasitology, College of medicine, University of Lagos, Lagos, Nigeria. | ||||
| Abstract | ||||
| The non-neoformans Cryptococci are increasingly causing opportunistic infections in both immunocompetent and immunocompromised individuals worldwide. Non. neoformans Cryptococci are skin and mucous membrane colonizers as well as environmental fungi. Cryptococcus laurentii and Cryptococcus albidus cause more than 80% of non-neoformans Cryptococcal infections are gaining recognition as human pathogens because of the advancements in diagnostic techniques. Here, we report 2 cases of C. laurentii fungaemia in an immunocompetent adult and a preterm neonate in Nigeria. The first case was a 51-year-old man with 31% second-degree mixed-thickness burns. He fully recovered with the addition of fluconazole early in its treatment. The second case was a preterm neonate in whom fungaemia was diagnosed after a fatal outcome had occurred. These two cases highlight that the new identification and susceptibility diagnostic techniques allow for earlier diagnosis and better treatment of unusual fungal infections. However, the timely and early commencement of empirical antifungal drugs improves patient outcomes. | ||||
| Keywords | ||||
| opportunistic infection; non-neoformans Cryptococci; Cryptococcus laurentii | ||||
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