The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.
Merdash, A., El-Sherbiny, G., Elgendy, A., Ahmed, M., El-Kabbany, H. (2023). The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.. EKB Journal Management System, 32(2), 65-71. doi: 10.21608/ejmm.2023.191693.1142
Ahmed G Merdash; Gamal M El-Sherbiny; Ahmed Osama Elgendy; Maged S Ahmed; Hussein M. El-Kabbany. "The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.". EKB Journal Management System, 32, 2, 2023, 65-71. doi: 10.21608/ejmm.2023.191693.1142
Merdash, A., El-Sherbiny, G., Elgendy, A., Ahmed, M., El-Kabbany, H. (2023). 'The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.', EKB Journal Management System, 32(2), pp. 65-71. doi: 10.21608/ejmm.2023.191693.1142
Merdash, A., El-Sherbiny, G., Elgendy, A., Ahmed, M., El-Kabbany, H. The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.. EKB Journal Management System, 2023; 32(2): 65-71. doi: 10.21608/ejmm.2023.191693.1142

The relation between antibiotic resistance pattern and the risk factors associated with urinary tract infections caused by E. coli.

Egyptian Journal of Medical Microbiology
Volume 32, Issue 2, April 2023, Page 65-71  XML PDF (337.74 K)
Document Type: New and original researches in the field of Microbiology.
DOI: 10.21608/ejmm.2023.191693.1142
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Authors
Ahmed G Merdash1; Gamal M El-Sherbiny email 2; Ahmed Osama Elgendy3; Maged S Ahmed4; Hussein M. El-Kabbany5
1Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Cai
2Al-Azhar University Faculty of Science
3Department of Microbiology, Faculty of Pharmacy – Beni-Suef University
4Botany and Microbiology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt
5Health Research Department, The National Center for Radiation Research and Technology, Atomic Energy Authority, Cairo, Egypt
Abstract
Background: Urinary tract infections (UTIs) are one of the most common bacterial infections which affect more than 150 million individuals each year worldwide. Objective: this study was conducted to assess the risk factors associated with urinary tract infections (UTIs) caused by resistant Escherichia coli. Methodology Four hundred and thirty urine samples were collected from outpatients who had urinary tract symptoms, ages ranging from 10 to 75 years in Beni-Suef Egypt, during a period extended from January 2021 to the end January 2022 and processed by standard microbiological methods. Results A total of 430 patients were included in this study, 210 (48.82%) uncomplicated and 220 (51.15%) complicated UTIs. Of 430 UTIs patients 287(66.8%) were females (77(36.6%) were complicated and 210(100%) uncomplicated), while 143 male UTIs patients were classified as complicated (65%). The prevalence of pathogenic microbes reveals bacterial species predominate in UTIs with 376 (87.42), E. coli high-frequency bacterial strains 85 (19.9), followed by Klebsiella sp. 70 (16.3), Pseudomonas aeruginosa 58 (13.5) and Enterococcus sp. 58 (13.5). Proteus mirabilis 46(10.9). Among 85 E coli isolates 46 from complicated and 39 isolates from uncomplicated UTIs patients showed the highest resistance to piperacillin/tazobactam 35(41.2%), sulfamethoxazole /trimethoprim 35 (41.2%), amoxicillin-clavulanic acid 34 (40%) and cefepime 34 (40%) and the least resistant antibiotics in the present study were colistin (3.5%), imipenem (5%), quinolones (5%) and nitrofurantoin (5%). Conclusion, nitrofurantoin, and quinoline remain still the best choice for treating complicated and uncomplicated UTI. Risk increases with the number of patients hospitalizations
Keywords
UTIs; E. coli; antimicrobial resistance; multivariate analysis
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