Ghost cell odontogenic carcinoma of the mandible: case report and review of literature | ||||
Egyptian Journal of Oral and Maxillofacial Surgery | ||||
Volume 13, Issue 4, October 2022, Page 193-195 PDF (488.12 K) | ||||
Document Type: Case Report | ||||
DOI: 10.21608/OMX.2023.180331.1180 | ||||
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Authors | ||||
Anouar ITOU* 1; Naouar OUATTASSI2; KAMAL Dounia3; EL Alami MN3 | ||||
1MD student ENT and Cervicofacial Surgery Department, Hassan II University Hospital Center, Fez | ||||
2Assistant Professor at ENT and Cervicofacial Surgery Department, Hassan II University Hospital Center, Fez | ||||
3Professor ENT and Cervicofacial Surgery Department, Hassan II University Hospital Center, Fez | ||||
Abstract | ||||
Introduction Ghost cell odontogenic carcinoma is described as an exceptionally rare malignant odontogenic tumor. The most characteristic histo logical feature is the presence of ghost cells; however the presence of ghost cells is not a specific feature. This article reports a mandibular case and documentes its clinico pathological features, hisological and radiological images and finally treatment received. Case report A 19-year-old female patient consulted for painful left cheek swelling, gradually increasing in volume. A 8 cm × 3 cm expansive mass was examined in the mandible, Physical examination revealed absence of molar contact on the left side with deviation of the lower dental arch on the contralateral side. Radiological assessment revealed a large, multi-compartmental osteolytic lesion of the left mandible, reaching upwards to the coronoid process and the temporal condyle. Histological examination of the surgical piece supported the diagnosis of ghost cell odontogenic carcinoma. Additional resection of the tumorous bone boundaries was performed. Then the decision of the multidisciplinary consultation meeting was to supplement the care with external radiotherapy. Discussion Ghost cell odontogenic carcinoma is very rare. The patient whose observation we report is particularly young. Clinical and radiological signs are not specific. The diagnosis is histological. The aggressive and recurrent nature requires radical wide surgery and close surveillance. | ||||
Keywords | ||||
odontogenic carcinoma; Ghost cell; mandible | ||||
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