Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.
Hafidh, Z., Abdelkader, A., Reda, B., Abdelkader, B., Kheira, B., lakhdar, Z. (2022). Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.. EKB Journal Management System, 14(2), 529-534. doi: 10.21608/eajbsc.2022.296475
Zemour Hafidh; Ammam Abdelkader; Belmamoun Ahmed Reda; Berrani Abdelkader; Boukabene Fouzia Kheira; Zemour lakhdar. "Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.". EKB Journal Management System, 14, 2, 2022, 529-534. doi: 10.21608/eajbsc.2022.296475
Hafidh, Z., Abdelkader, A., Reda, B., Abdelkader, B., Kheira, B., lakhdar, Z. (2022). 'Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.', EKB Journal Management System, 14(2), pp. 529-534. doi: 10.21608/eajbsc.2022.296475
Hafidh, Z., Abdelkader, A., Reda, B., Abdelkader, B., Kheira, B., lakhdar, Z. Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.. EKB Journal Management System, 2022; 14(2): 529-534. doi: 10.21608/eajbsc.2022.296475

Anti-inflammatory and Antibacterial Activity of the Methanol Extract of Artemisia Herba-Alba.

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology
Volume 14, Issue 2, December 2022, Page 529-534  XML PDF (379.65 K)
Document Type: Original Article
DOI: 10.21608/eajbsc.2022.296475
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Authors
Zemour Hafidh1; Ammam Abdelkader2; Belmamoun Ahmed Reda3; Berrani Abdelkader4; Boukabene Fouzia Kheira5; Zemour lakhdar6
1Faculty of Natural and Life Sciences, Ibn Khaldoun University, BP 14000, Tiaret; Algeria.
2Laboratory of Pharmacognosy, Bio toxicology, and Biological Valorization of Plants, Moulay Tahar University, BP 20000, Saida, Algeria.
3Laboratory of Process, materials and environmental engineering, Djillali Liabes University, BP 22000, Sidi-Bel-Abbes, Algeria.
4Ibn Khaldoun University, BP 14000, Tiaret; Algeria.
5Laboratory of sciences and technics of animal production, Mostaghanem, Moulay Tahar University, BP 20000, Saida, Algeria.
6Faculty of medicine, Oran, Algeria.
Abstract
The use of medicinal plants from the traditional African pharmacopoeia in the treatment of various diseases has been known for a long time, and the positive effects of this phytotherapy are no longer in question. However, these practices are based on empiricism. The methanolic extract of the leaves of Artemisia herba-alba has analgesic and anti-inflammatory properties that justify its traditional use. This study evaluates the anti-inflammatory and antibacterial properties of the methanolic leaf extract of Artemisia herba-alba. The negative control and test groups received 40 mg/kg of the extract. The anti-hematogenic effects of the extract showed a significant decrease in carrageenan-induced paw edema at 1 and 3 hours, as well as dextran-induced inflammation, compared to the control. In addition, there was inhibition of xylene-induced ear edema with a significant reduction compared to the control (p<0.05). The bacterial activity was determined on five bacterial strains: Klebsiella pneumoniae ATCC700603, Citrobacter freindii ATCC8090, Salmonella typhii ATCC13311, Enterobacter coloacae ATCC13047 and Staphylococcus aureus ATCC25923, according to the in vitro agar diffusion method (aromatogram). Our extract would therefore be an advantageous source of improved traditional medicine that is accessible and less expensive for people.
Keywords
Anti-inflammatory; antibacterial; methanol extract; Artemisia herba-alba
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