Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso
Zoure, A., Ouedraogo, H., Soubeiga, S., Compaoré, T., Zida, S., Ouedraogo, O., Kambiré, D., Zingue, D., Dabiré, C., KAGAMBEGA, A., Sawadogo, C., Yabre, Z., SAGNA, T., Sangare, L. (2023). Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso. EKB Journal Management System, 4(3), 713-723. doi: 10.21608/mid.2023.205094.1507
Abdou Azaque Zoure; Henri Gautier Ouedraogo; Serge Théophile Soubeiga; Tegwinde Rebeca Compaoré; Sylvie Zida; Oumarou Ouedraogo; Dinanibè Kambiré; Dezemon Zingue; Charlemagne Dabiré; Alidou KAGAMBEGA; Charles Sawadogo; Zakariya Yabre; Tani SAGNA; Lassana Sangare. "Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso". EKB Journal Management System, 4, 3, 2023, 713-723. doi: 10.21608/mid.2023.205094.1507
Zoure, A., Ouedraogo, H., Soubeiga, S., Compaoré, T., Zida, S., Ouedraogo, O., Kambiré, D., Zingue, D., Dabiré, C., KAGAMBEGA, A., Sawadogo, C., Yabre, Z., SAGNA, T., Sangare, L. (2023). 'Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso', EKB Journal Management System, 4(3), pp. 713-723. doi: 10.21608/mid.2023.205094.1507
Zoure, A., Ouedraogo, H., Soubeiga, S., Compaoré, T., Zida, S., Ouedraogo, O., Kambiré, D., Zingue, D., Dabiré, C., KAGAMBEGA, A., Sawadogo, C., Yabre, Z., SAGNA, T., Sangare, L. Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso. EKB Journal Management System, 2023; 4(3): 713-723. doi: 10.21608/mid.2023.205094.1507

Performance assessment of StandardTM Q COVID-19 Ag Test in Ouagadougou, Burkina Faso

Microbes and Infectious Diseases
Article 2, Volume 4, Issue 3, August 2023, Page 713-723  XML PDF (879.62 K)
Document Type: Original Article
DOI: 10.21608/mid.2023.205094.1507
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Authors
Abdou Azaque Zoure email orcid 1; Henri Gautier Ouedraogoorcid 1; Serge Théophile Soubeigaorcid 1; Tegwinde Rebeca Compaoréorcid 1; Sylvie Zidaorcid 1; Oumarou Ouedraogoorcid 1; Dinanibè Kambiréorcid 1; Dezemon Zingueorcid 2; Charlemagne Dabiré1; Alidou KAGAMBEGA1; Charles Sawadogo3; Zakariya Yabre3; Tani SAGNAorcid 1; Lassana Sangareorcid 4
1Département Biomédical et Santé Publique, Institut de Recherche en Sciences de la Santé /National Centre for Scientific and Technologic Research (IRSS/CNRST), Ouagadougou, Burkina Faso
2Institut National de Santé Publique (INSP), Ministère de la Santé, Ouagadougou, Burkina Faso
3Direction des Laboratoires de Biologie Médicale (DLBM), Ministère de la santé et de l’Hygiène publique, Ouagadougou, Burkina Faso
4Unité de Formation et de Recherche en Sciences de la Santé (UFR-SDS), Université Joseph Ki-Zerbo, Ouagadougou, Burkina Faso
Abstract
Background: Many rapid antigen kits for SARS-CoV-2 detection have been developed and the results interpreted usually within 30 minutes. Antigen tests are recommended to be used in areas where access to the PCR method is limited, as is the case in Burkina Faso. The aim of this study is to assess the performance of "Standard TM Q COVID-19 Ag Test " in the detection of SARS-CoV-2 antigen. Methods: The evaluation was performed using swabs samples collected between January 26 and March 31, 2021, from 201 subjects previously diagnosed by RT-PCR.  The performance of the rapid test “Standard TM Q COVID-19 Ag Test was compared to the RT-PCR test “STANDARD M nCoV real-time detection kit”. Results: Of these 201 samples, 16 were positive for the COVID-19 RT-PCR, and 185 were negative. The sensitivity of the "Standard TM Q COVID-19 Ag Test" was 100% (IC95%: 34.24- 100) in symptomatic subjects with a symptom onset time of 1 to 5 days. This sensitivity decreased to 66.67% (IC95%: 20.77- 93.85) in symptomatic subjects with a symptom onset time of 1 to 7 days. The specificity, it was 95% (IC95%: 83.5-98.62) in all symptomatic subjects and 93.75% (IC95%: 79.85-98.2) in subjects whose symptoms appeared between 1 and 5 days. Conclusion: The " Standard TM Q COVID-19 Ag Test " was better in subjects with delayed symptoms up to 5 days. However, this kit was not suitable for COVID-19 detection in asymptomatic subjects.
Keywords
COVID-19; SARS-CoV-2; Diagnosis; Antigen test; Burkina Faso
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