Mycobiota associated with teeth and oral cavity and their relevant to dental and periodontal diseases | ||||
| Assiut University Journal of Multidisciplinary Scientific Research | ||||
| Volume 52, Issue 2, May 2023, Page 195-231 PDF (1.12 MB) | ||||
| Document Type: Novel Research Articles | ||||
| DOI: 10.21608/aunj.2023.202022.1047 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Asmaa Mohamed Nasr   1; Mohamed Ahmed Abdel-Sater1; Nemmat Abdel-Gawad Hussein2; Amal Daniala3; Mohamed F. Edrees4
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| 1Botany and Microbiology Department, Faculty of Science, Assiut University, P.O. Box 71526, Assiut, Egypt | ||||
| 2Department of Botany and Microbiology, Faculty of Science, Assiut University, Assiut, Egypt | ||||
| 31Botany and Microbiology Department, Faculty of Science, Assiut University, P.O. Box 71526, Assiut, Egypt | ||||
| 4Oral Medicine and Periodontology Department, Faculty of Dentistry, Al-Azhar University, Assiut Branch, Egypt | ||||
| Abstract | ||||
| Teeth and oral cavity harbor diverse community of fungi and bacteria. Little is known about fungal community of oral cavity, teeth and gingiva. In this study, fungal diversity in various sites was evaluated using Sabouraud dextrose agar (SDA). Sixty swabs samples from patients suffering from gingivitis, periodontitis and dental caries in addition to healthy persons as control (15 each) were collected for fungal analyses. Thirteen fungal species related to 7 genera were isolated and identified. To the best of our knowledge, Candida ciferrii and Cryptococcus laurentii were recorded for the first time from the oral cavity in the current study. There is a highly significant variation in the frequency of Aspergillus niger and Candida ciferrii among isolated fungi. Screening of the yeast isolates for extra-cellular enzymes production resulted in 47.2% (34 out of 72 isolates) of the tested isolates showed positive lipolytic activities with varying capabilities; whereas 41 isolates (56.9%) were positive protease producers. Also, the antimicrobial activity of some toothpastes, mouth washes, natural oils and pharmaceutical preparations against yeast species were performed. Among the tested substances, Paradontax, Hexitol and Clove oil showed the best antimicrobial activity against the tested yeast isolates. The minimum inhibition concentration (MICs) of Hexitol was high compared to Paradontax and Clove oil. This study provided clear image about fungal content in mouth, teeth and gingiva, the relation of these fungi in case of health or disease was also discussed. | ||||
| Keywords | ||||
| Candida ciferrii; Cryptococcus laurentii; Lipase; Protease; Hexitol | ||||
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