A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section
Sweed, A., Khlaiq, S., Shehata, H., Taema, M. (2023). A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section. EKB Journal Management System, 27(2), 9-15. doi: 10.21608/egyfs.2023.297235
Amr Sobhy Sweed; Shahida Khlaiq; Hanan Shehata; Mohamed I Taema. "A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section". EKB Journal Management System, 27, 2, 2023, 9-15. doi: 10.21608/egyfs.2023.297235
Sweed, A., Khlaiq, S., Shehata, H., Taema, M. (2023). 'A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section', EKB Journal Management System, 27(2), pp. 9-15. doi: 10.21608/egyfs.2023.297235
Sweed, A., Khlaiq, S., Shehata, H., Taema, M. A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section. EKB Journal Management System, 2023; 27(2): 9-15. doi: 10.21608/egyfs.2023.297235

A prospective comparative study between tramadol, lidocaine and placebo in subcutaneous wound infiltration for postoperative pain relief in cesarean section

The Egyptian Journal of Fertility of Sterility
Article 3, Volume 27, Issue 2 - Serial Number 11106352, March 2023, Page 9-15  XML PDF (2.28 MB)
Document Type: Original Article
DOI: 10.21608/egyfs.2023.297235
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Authors
Amr Sobhy Sweed email 1; Shahida Khlaiq2; Hanan Shehata3; Mohamed I Taema3
1Lecturer of Obstetrics and Gynecology Faculty of medicine, Ain Shams University, Cairo-Egypt
2Department of obstetrics and gynecology, Faculty of medicine, King Saud University, Riyadh, Saudi Arabia
3Department of obstetrics and gynecology, Ain shams university. Cairo Egypt
Abstract
Background: As the rate of cesarean section (CS) is increasing rapidly, the need of postoperative analgesia is increasingly required. Aim: to evaluate the effect of tramadol injection at incision site before closure of the skin in patients undergoing cesarean section on post-operative pain and the need of analgesics in comparison to lidocaine.
Methods: this study was conducted in 2 hospitals in kingdom of Saudi Arabia in period of January 2021 till June 2021, ninety women undergoing cesarean section delivery were divided into 3 groups to receive tramadol, lidocaine or placebo subcutaneously before closing of skin in CS. using visual analogue scale (VAS), Pain was assessed at 6, 12 and 24 h post-operative.
Results: Pain (VAS scores) were significantly lower in the tramadol group in comparison to the other two groups at 6 h (p<0.001), and 12 h (p<0.01). VAS score at 24 h was significantly lower in the Tramadol group compared with Placebo group (p<0.01) and was comparable to Lidocaine group. Non statistically significant difference between VAS scores in Lidocaine group and Placebo was. Time to first analgesic demand was significantly longer in Tramadol group; 2.58±0.93 versus 2.47±0.82 versus 5.97±3.19 hours in the Placebo, Lidocaine and Tramadol group respectively, p <0.001.
Conclusion : local wound injection with tramadol resulted in significantly lower pain scores, But longer time to first analgesic request and lower overall cumulative 24-hour consumption of analgesics. Lidocaine didn’t add any analgesic effect over placebo. tramadol wound injection in CS is a good choice for post-operative analgesia.
Keywords
Lidocaine; post cesarean section analgesia; post operative pain; tramadol
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