ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?
MORSY, T., HAWAM, S., HADIDY, H., AHMED, S. (2023). ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?. EKB Journal Management System, 53(1), 35-50. doi: 10.21608/jesp.2023.297342
TOSSON A. MORSY; SARYA MOHAMED HAWAM; HAITHAM A. El HADIDY; SHERIF AHMED MEGAHED AHMED. "ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?". EKB Journal Management System, 53, 1, 2023, 35-50. doi: 10.21608/jesp.2023.297342
MORSY, T., HAWAM, S., HADIDY, H., AHMED, S. (2023). 'ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?', EKB Journal Management System, 53(1), pp. 35-50. doi: 10.21608/jesp.2023.297342
MORSY, T., HAWAM, S., HADIDY, H., AHMED, S. ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?. EKB Journal Management System, 2023; 53(1): 35-50. doi: 10.21608/jesp.2023.297342

ZOONOTIC BARTONELLOSIS: IS IT THRERATING TO THE EASTERN MEDITERRANEAN COUNTRIES?

Journal of the Egyptian Society of Parasitology
Volume 53, Issue 1, April 2023, Page 35-50  XML PDF (1.07 MB)
DOI: 10.21608/jesp.2023.297342
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Authors
TOSSON A. MORSY1; SARYA MOHAMED HAWAM2; HAITHAM A. El HADIDY3; SHERIF AHMED MEGAHED AHMED4
1Department of Parasitology, Faculty of Medicine
2Department of Microbiology, Military Medical Academy, Cairo, 11291
3Hospital Administration, School of Medicine, Badr University
4Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, 11566
Abstract
Bartonellosis is a group of emerging and re-emerging bacteria of Bartonella genus with worldwide
distribution. Bartonella species cause diseases such as Carrión's disease, trench fever, cat
scratch disease, bacillary angiomatosis, peliosis hepatis, chronic bacteremia, endocarditis, chronic
lymphadenopathy, and neurological disorders. Fleas, lice, sand-flies, bed bugs, ticks, mites,
and even spiders transmit infection to man, domestic and wild animals. Infection is establishing
intracellular replication niches and subverts diverse pathways of host's immune system. Bartonellosis
can subclinical bacteremia to broad spectrum of clinical symptoms in man ranged from a
mild flu-like intermittent fever to more severe manifestations such as, arthralgia, arthritis, endocarditis,
hepatitis, myocarditis, neuroretinitis, uveitis, vasoproliferative tumors and even death.
Effective antibiotics include rifampin, ciprofloxacin, gentamicin, and trimethoprim/sulfamethoxazole.
But, B. henselae is generally resistant to penicillin, amoxicillin, and nafcillin. Doxycycline
and rifampin in combination are recommended to treat neuroretinitis. Treatment must be
adapted to each clinical situation, species, and acute or chronic disease, but in a timely manner
Keywords
Bartonellosis; Man; Animals; Vectors; Pathogenesis; Diagnosis; Treatment
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