SPONTANEOUS BACTERIAL PERITONITIS PROFILE IN DECOMPENSATED CIRRHOTIC EGYPTIAN PATIENTS | ||||
Journal of the Egyptian Society of Parasitology | ||||
Volume 53, Issue 1, April 2023, Page 51-56 PDF (686.23 K) | ||||
DOI: 10.21608/jesp.2023.297343 | ||||
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Authors | ||||
SAMAR ATEF SEBAWEH1; HASSAN S. HAMDY1; AMIRA AL BALAKOSY1; HEND MUBARAK1; MOHAMMED SOBHI HASSAN2; LINA ESSAM KHEDR3 | ||||
1Department of Tropical Medicine | ||||
2Department of Radiodiagnosis | ||||
3Department of Internal Medicine , Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt | ||||
Abstract | ||||
Bacterial infections are common and life-threatening in cirrhotic patients with ascites. Among patients who survived the first episode of SBP, about 70% experienced a recurrence within a year. Bacterial causative agent(s) and response to treatment were evaluated in 104 decompensated cirrhotic patients with ascites who were presented to Tropical Medicine Department, Ain Shams University Hospitals from February 2019 to June 2022 were evaluated for incidence of SBP, bacterial causative agent(s) and response to treatment. They were divided into two groups: GA received Rifaximin (N=52) and GB received Norfloxacin (N=52), Diagnostic paracentesis was done as needed for ascitic fluid analysis and culture, clinical and bacteriological profile of SBP was recorded. The results showed that the ascitic fluid infection in patients was 28.8% in both group, with symptoms of abdominal pain (100%) and fever (63.3%). Culture negative neutrocytic ascites (CNNA) was in 63.33%, Monomicrobial non neutrocytic bacterascites was in 33.3% and polymicrobial ones was in 3.33%. The isolated bacteria were E. coli and Staph. coagulase negative, of 30 % in each group. | ||||
Keywords | ||||
Patients; Ascites; Spontaneous bacterial peritonitis; Rifaximin; Norfloxacin | ||||
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