Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction
El-Fayomy, A., Abdelsalam, W., Mohamed, A., Mostafa, M. (2023). Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction. EKB Journal Management System, 91(1), 4648-4653. doi: 10.21608/ejhm.2023.297799
Amr Kamel El-Fayomy; Walid Abdallah Abdelsalam; Ahmed Ismail Mohamed; Mostafa Ahmed Mostafa. "Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction". EKB Journal Management System, 91, 1, 2023, 4648-4653. doi: 10.21608/ejhm.2023.297799
El-Fayomy, A., Abdelsalam, W., Mohamed, A., Mostafa, M. (2023). 'Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction', EKB Journal Management System, 91(1), pp. 4648-4653. doi: 10.21608/ejhm.2023.297799
El-Fayomy, A., Abdelsalam, W., Mohamed, A., Mostafa, M. Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction. EKB Journal Management System, 2023; 91(1): 4648-4653. doi: 10.21608/ejhm.2023.297799

Study of Role of Maternal Serum Ferritin in the Prediction of Asymmetric Intrauterine Growth Restriction

The Egyptian Journal of Hospital Medicine
Article 137, Volume 91, Issue 1, April 2023, Page 4648-4653  XML PDF (468.91 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2023.297799
View on SCiNiTO View on SCiNiTO
Authors
Amr Kamel El-Fayomy; Walid Abdallah Abdelsalam; Ahmed Ismail Mohamed; Mostafa Ahmed Mostafa
Abstract
Background: Late-onset asymmetric Intrauterine Growth Restriction (IUGR) is associated with an increase in the maternal serum ferritin level, which is thought to be caused by a decrease in placental extraction ferritin from the systemic circulation. Objective: The aim of the current study was to predict asymmetric IUGR by measuring maternal serum ferritin at 30-32 weeks of gestation. Patients and methods: A cross sectional study was conducted on a total of 550 women. At 30-32 weeks of gestation, maternal serum ferritins were assessed. Of the studied women, 84 women were selected and divided into two groups; 42 cases of elevated serum ferritin level taken as a case group and the first included 42 cases with normal serum ferritin level served as a control group. At 30-32 weeks of gestation, we assessed maternal serum ferritin. Results: Serum ferritin is good marker for detecting cases of IUGR at cut off ≥12.45 with a sensitivity of 85.7%, a specificity of 35.7%, a positive predictive value of 57.1% and a negative predictive value of 71.4%., while serum ferritin is good marker for excluding cases of IUGR at cut off ≥20.5 with a sensitivity of 33.3%, a specificity of 85.7%, a positive predictive value of 70% and a negative predictive value of 56.3%.
Conclusion: Serum ferritin level with a cut off level ≥12.45 ng/dl in addition to ultrasonography has as a predictive value of asymmetric IUGR
 
Keywords
Serum Ferritin; Ultrasonography; Asymmetric Intrauterine Growth Restriction
Statistics
Article View: 107
PDF Download: 246