A Review on High Fat Diet-Induced Obesity and Natural Compounds' Role in the Management of Obesity | ||||
| Egyptian Journal of Chemistry | ||||
| Volume 66, Issue 13, December 2023, Page 763-774 PDF (585.13 K) | ||||
| Document Type: Review Articles | ||||
| DOI: 10.21608/ejchem.2023.185352.7420 | ||||
 View on SCiNiTO | ||||
| Author | ||||
Sahar Khateeb  1, 2
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| 1Department of Biochemistry, Faculty of Science, University of Tabuk, 71491, Saudi Arabia | ||||
| 2Biochemistry Division, Department of Chemistry, Faculty of Science, Fayoum University, Fayoum, Egypt | ||||
| Abstract | ||||
| Obesity is a global problem that causes severe health problems. Since, it increases the risk of developing chronic diseases, such as cardiovascular diseases, cancer, and type 2 diabetes. Pharmacotherapy is still the mainstay for managing obesity, but its efficacy is inadequate, it is non-specific, and it has harmful side effects, so its usefulness is limited. Therefore, it is essential to create new anti-obesity therapy methods or enhance currently available medications, in addition, novel ways could offer insights into obesity and obesity-associated disorders. Natural products, particularly plant extracts, are viewed as an alternative because they have no negative side effects. Plant extracts, in particular, contain antioxidant, anti-inflammatory, and insulin-sensitizing characteristics. Moreover, nanotechnology is one of the promising methods for increasing therapeutic efficacy and improving the anti-obesity effectiveness of these natural chemicals due to their alleged ability to be target-specific. Nanotechnology makes natural chemicals more bioavailable, biodistributable, stable, and soluble. This makes it a promising way to treat obesity. | ||||
| Keywords | ||||
| Keywords: adipose tissue; plant extracts; nanotechnology; obesity | ||||
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