Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study
Idris, O., Mustapha, Y., Yusuff, O., Sani, M., Afolabi, A., Omokanye, H., Quadri, R., Biliaminu, A., Wuraola, O., Nicolas, B., Mainasara, M., Ahmad, A., Joseph, Y., Sani, A., Iyanda, N., Oladosu, W., Inoh, I., Onyema, C. (2023). Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study. EKB Journal Management System, 24(24), 1-5. doi: 10.21608/ejentas.2022.95204.1418
Olanrewaju Sa'ad Idris; Yaro Abubakar Mustapha; Omokunmi Jameelu-deen Yusuff; Mohammad Sani; Abdulrahman Afolabi; Habeeb Kayode Omokanye; Raheem Oladeji Quadri; Abayomi Sikiru Biliaminu; Ololade Wuraola; Bemu Alfred Nicolas; Muhammad Garba Mainasara; Ali Ahmad; Yohanna Joseph; Adamu Sani; Nurudeen Iyanda; Waliu Olatunbosun Oladosu; Ime Mfon Inoh; Chinazo 0. Onyema. "Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study". EKB Journal Management System, 24, 24, 2023, 1-5. doi: 10.21608/ejentas.2022.95204.1418
Idris, O., Mustapha, Y., Yusuff, O., Sani, M., Afolabi, A., Omokanye, H., Quadri, R., Biliaminu, A., Wuraola, O., Nicolas, B., Mainasara, M., Ahmad, A., Joseph, Y., Sani, A., Iyanda, N., Oladosu, W., Inoh, I., Onyema, C. (2023). 'Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study', EKB Journal Management System, 24(24), pp. 1-5. doi: 10.21608/ejentas.2022.95204.1418
Idris, O., Mustapha, Y., Yusuff, O., Sani, M., Afolabi, A., Omokanye, H., Quadri, R., Biliaminu, A., Wuraola, O., Nicolas, B., Mainasara, M., Ahmad, A., Joseph, Y., Sani, A., Iyanda, N., Oladosu, W., Inoh, I., Onyema, C. Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study. EKB Journal Management System, 2023; 24(24): 1-5. doi: 10.21608/ejentas.2022.95204.1418

Prevalence of Hypovitaminosis D among ENT Patients in Nigeria – A Multi-center, Multi-regional study

Egyptian Journal of Ear, Nose, Throat and Allied Sciences
Article 48, Volume 24, Issue 24, January 2023, Page 1-5  XML PDF (274.73 K)
Document Type: Original Article
DOI: 10.21608/ejentas.2022.95204.1418
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Authors
Olanrewaju Sa'ad Idris email orcid 1; Yaro Abubakar Mustapha2; Omokunmi Jameelu-deen Yusuff3; Mohammad Sani4; Abdulrahman Afolabi5; Habeeb Kayode Omokanye6; Raheem Oladeji Quadri7; Abayomi Sikiru Biliaminu3; Ololade Wuraola8; Bemu Alfred Nicolas4; Muhammad Garba Mainasara4; Ali Ahmad7; Yohanna Joseph4; Adamu Sani9; Nurudeen Iyanda10; Waliu Olatunbosun Oladosu11; Ime Mfon Inoh12; Chinazo 0. Onyema13
1Consultant ENT Surgeon, University of Ilorin Teaching Hospital, Ilorin, Nigeria
2Consultant ENT Surgeon, National Ear Care Centre (NECC), Kaduna, Kaduna State, North-West, Nigeria
3Consultant Chemical Pathologist, Department of Chemical Pathology, University of Ilorin Teaching Hospital, Ilorin, North-Central Nigeria
4Consultant ENT Surgeon, National Ear Care Centre (NECC) Kaduna, Kaduna, North-West Nigeria.
5Consultant ENT Surgeon, Department of ENT, University of Ilorin Teaching Hospital, Ilorin, North-Central Nigeria
6Consultant ENT Surgeon, Department of ENT, University of Ilorin Teaching Hospital, Ilorin, North-Central Nigeria.
7Consultant ENT Surgeon, Department of ENT Surgery, ENT unit, Federal Teaching Hospital (FTH), Gombe, North East Nigeria.
8Senior Resident ENT, Department of ENT, University of Ilorin Teaching Hospital, Ilorin, North-Central Nigeria.
9Consultant Chemical Pathologist, Department of Chemical Pathology, Federal Teaching Hospital, Gombe, Gombe State.
10Consultant ENT Surgeon, Department of ENT, Federal Medical Centre Abeokuta, Abeokuta, Ogun State South-Western Nigeria.
11Consultant Chemical Pathologist, Department of Pathology, Federal Medical Centre Abeokuta, Abeokuta, Ogun State South-Western Nigeria.
12Consultant ENT Surgeon, Department of ENT Surgery, University of Uyo Teaching Hospital, Uyo, Akwa-Ibon State.
13Consultant ENT Surgeon, Department of ENT Surgery, FMC Owerri, Imo State.
Abstract
Objective: Vitamin D are fat-soluble hormones with various biological effects in the body. Exposure to Sunlight remains the primary determinant of vitamin D status in humans. Despite abundant sunshine in northern Nigeria, high prevalence of vitamin D deficiency has been reported. Hence, this study aimed to determine the prevalence of vitamin D deficiency among patients attending ENT clinics in Nigeria.
Patients and Methods: A multi-centre, case-control study carried out among ENT patients attending selected tertiary hospitals in northern Nigeria and healthy controls. The study locations and participants were selected using a multi-stage sampling technique. Consecutive consenting patients attending ENT clinics responded to interviewer-administered questionnaires. Serum vitamin D was determined using Calbiotech 25(OH) vitamin D ELISA kit.
Results: Age range of the 198 participants was 2-70 years. Median ages was 31.0 and 31.5 years for subjects and controls respectively. Modal age group was 31-40 years. There were 62.1% female participants with Male to Female ratio of 1:1.6. Prevalence of Hypovitaminosis D was higher among subjects than controls. (p=0.034) More females had deficient (87.5%) and insufficient (73.1%) levels of vitamin D compared with their male counterparts (12.5%) and (26.9%) respectively. (p= 0.009) Subjects with dark skin colour had lower mean vitamin D level (34.8 versus 39.8nmol/L). (p=0.006).
Conclusion: Patients attending general Otorhinolaryngology clinics in northern Nigeria had low vitamin D levels and its supplementation may go a long way in optimizing their primary condition. Female gender and dark skin colour were important factors that contribute to low vitamin D level. Vitamin D supplements may be useful as prophylactics and adjunct treatment for common otorhinolaryngological conditions.
Keywords
Case-Control studies; Nigeria; tertiary care centres; vitamin D
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