ANTIOXIDANT, ANTIDIABETIC, ANTIBACTERIAL, AND ANTICANCER ACTIVITIES OF EGYPTIAN FENUGREEK | ||||
| Sinai Journal of Applied Sciences | ||||
| Article 6, Volume 12, Issue 3, May and June 2023, Page 423-432 PDF (956.09 K) | ||||
| Document Type: Researches | ||||
| DOI: 10.21608/sinjas.2023.199738.1195 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Eman M. Abdalla  1; Shaimaa R. Hatab1; Hany G. El-Masry2; Mamdouh K. Metwally1
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| 1Dept. Food and Dairy Sci. and Techno., Fac. Enviro. Agric. Sci., Arish Univ., North Sinai, Egypt. | ||||
| 2Dept. Nutr. and Food Sci., Fac. Home Econ., Helwan Univ., Egypt. | ||||
| Abstract | ||||
| Fenugreek (FG) flour is a common plant used in Egypt to add flavour and colour to food, keep food fresh, and as a medicine. The current study tested FG for its antioxidant, antidiabetic, antimicrobial and anticancer activities. FG showed significant contents of phenolic and flavonoid compounds, reflecting their nutraceutical behaviors. The EC50 of FG when tested for its DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging was 2476 ± 62.9 µg/mL, while the FG extract’s concentration that inhabited ABTS (2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)) was 37.13 ± 1.24 µg/mL. FG could lower blood sugar, as it showed an alpha-glucosidase inhibiton at EC50 > 1000 µg/mL. Almost 99% of breast cancer cells were damaged by FG extract concentrations > 100 μg/mL. FG extract was successful in antimicrobial activity against Escherichia coli ATCC 8739 at a 1000 µg/mL concentration. The current study showed the promising usage of FG as a functional additive to different foods. | ||||
| Keywords | ||||
| Fenugreek; Antioxidant; Antidiabetic; Antibacterial; Anticancer | ||||
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