Screening for drug misusers in exacerbated chronic obstructive pulmonary disease (COPD) patients | ||||
Medicine Updates | ||||
Article 2, Volume 14, Issue 14, July 2023, Page 1-19 PDF (1019.37 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/muj.2023.209496.1139 | ||||
View on SCiNiTO | ||||
Authors | ||||
Eman M Mahmoud 1; Zeinab Abdou Mohammed2; Abeer El hawary3; Dalia Ans Ibrahim4 | ||||
1PORT SAID UNIVERSIY | ||||
2Assistant professor of toxicology faculty of medicine Zagazig university | ||||
3Assistant professor of Chest diseases faculty of medicine Zagazig university | ||||
4Assistant professor of Chest medicine Zagazig university | ||||
Abstract | ||||
Background: Even though treatment for chronic obstructive pulmonary disease (COPD) has improved, COPD exacerbation-related complications remain challenging. One related factor is substance use/abuse .Generally there is a rising concern about COPD with substance use to decrease the burden on health care because of substance use associated complications We, therefor aimed to asses the secondary morbidity, frequency of exacerbation and the need for Mechanical ventilation related to substance misuse in chronic obstructive lung disease patients . Methods and Material: This is cohort population –based study on 50 acute exacerbated COPD patients who were admitted to intensive care unit of Chest department, Zagazig University Hospitals during the period from February 2021to march 2022.After taking an informed consent from them they were classified into two groups Drug abusers group and non drug abusers group Results: : In between drug abusers group, opioids were the most prevalent misused substance (63%)). Also, there was statistical significance difference between both patients groups as regards frequency of exacerbation, drug abusers significantly associated with higher rate of exacerbation, higher type II respiratory failure and higher rate of need for MV Conclusions:Diagnosis of substance misuse was associated with increased risk of respiratory failure, increased frequency of exacerbation and the need for mechanical ventilation . | ||||
Keywords | ||||
COPD; respiratory failure; drug abuse; opiates | ||||
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