Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function
Ghanem, I., Dwedar, A., Marwad, A., Gouda, M. (2023). Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function. EKB Journal Management System, 29(5), 1448-1455. doi: 10.21608/zumj.2023.212305.2805
Islam Ghanem; Ashraf AlSeed Dwedar; Ahmed Reda Abdelrahman Marwad; Mohammad Gouda. "Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function". EKB Journal Management System, 29, 5, 2023, 1448-1455. doi: 10.21608/zumj.2023.212305.2805
Ghanem, I., Dwedar, A., Marwad, A., Gouda, M. (2023). 'Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function', EKB Journal Management System, 29(5), pp. 1448-1455. doi: 10.21608/zumj.2023.212305.2805
Ghanem, I., Dwedar, A., Marwad, A., Gouda, M. Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function. EKB Journal Management System, 2023; 29(5): 1448-1455. doi: 10.21608/zumj.2023.212305.2805

Atrial Electro-Mechanical Asynchrony As A Predictor Of Cerebrovascular Stroke In Patients With Sinus Rhythm And Normal Left Ventricular Systolic Function

Zagazig University Medical Journal
Article 27, Volume 29, Issue 5, September and October 2023, Page 1448-1455  XML PDF (457.41 K)
Document Type: Original Article
DOI: 10.21608/zumj.2023.212305.2805
View on SCiNiTO View on SCiNiTO
Authors
Islam Ghanem email orcid 1; Ashraf AlSeed Dwedar2; Ahmed Reda Abdelrahman Marwad3; Mohammad Gouda4
1Lecturer of Cardiology, Faculty of medicine, Zagazig university
2Professor, Cardiology, Zagazig
3Resident, ElAhrar teaching hospital, Zagazig, Egypt
4Assistant Professor
Abstract
Background: Atrial cardiopathy is a risk factor for cerebrovascular stroke. Greater LA size is linked to stroke in AF patients, but few data regarding population with sinus rhythm.

Aim: To investigate PA-TDI duration as a predictor of stroke in patients who initially presented with sinus rhythm and have normal LV systolic function.

Patients and methods: In our case-control study, we studied patients admitted to Zagazig university hospital with acute ischemic stroke. It included 156 patients with acute ischemic stroke and 50 control subjects. The left atrial diameter and left atrial volume index were assessed. The PA-TDI mean interval was assessed.

Results: There was no statistically significant difference between both groups regarding LA diameter (p: 0.3), LA volume index was larger in the stroke group (p: 0.01), PA-TDI duration was highly significant difference between both groups (165.94±21.695 versus 99.4±22.960, p: <0.001). ROC curve showed the best cutoff point for LA volume index is >42.2 ml/m2 for prediction of stroke with 52.8 % sensitivity, 80.8% specificity, p value is 0.005. ROC curve showed the best cutoff point for PA-TDI is >155.5 ms for prediction of stroke with p value: <0.001. Using multivariate logistic regression analysis showed that hypertension, LA volume index and PA-TDI duration are independent predictors of stroke (p: < 0.05, < 0.05, and < 0.001 respectively).

Conclusion: The assessment of electromechanical asynchrony by measuring the PA-TDI duration in population with sinus rhythm may help to predict patients at risk for stroke and thus may benefit from anticoagulant therapy.
Keywords
Atrial asynchrony; Cerebrovascular stroke; Sinus rhythm
Statistics
Article View: 175
PDF Download: 65