Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.
Mohamed, M., Abdelatif, R., Bakheet, M., Mahmoud, R. (2023). Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.. EKB Journal Management System, 27(2), 95-104. doi: 10.21608/smj.2023.206040.1383
Montaser Mohamed Mohamed; Rania Gamal Abdelatif; Mohamed Abdel Aal Mohamed Bakheet; Ramadan Aboelhassan Ahmed Mahmoud. "Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.". EKB Journal Management System, 27, 2, 2023, 95-104. doi: 10.21608/smj.2023.206040.1383
Mohamed, M., Abdelatif, R., Bakheet, M., Mahmoud, R. (2023). 'Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.', EKB Journal Management System, 27(2), pp. 95-104. doi: 10.21608/smj.2023.206040.1383
Mohamed, M., Abdelatif, R., Bakheet, M., Mahmoud, R. Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.. EKB Journal Management System, 2023; 27(2): 95-104. doi: 10.21608/smj.2023.206040.1383

Performance of pediatric index of mortality-2, pediatric index of mortality-3 and pediatric risk of mortality IV in an Egyptian pediatric intensive care unit.

Sohag Medical Journal
Volume 27, Issue 2, 2023, Page 95-104  XML PDF (706.83 K)
Document Type: Original Article
DOI: 10.21608/smj.2023.206040.1383
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Authors
Montaser Mohamed Mohamed1; Rania Gamal Abdelatif email orcid 2; Mohamed Abdel Aal Mohamed Bakheet3; Ramadan Aboelhassan Ahmed Mahmoud4
1pediatric,medicine,sohag university,egypt
2Pediatric department, Faculty of Medicine, Sohag University, Egypt
3pediatric Department, Faculty of Medicine, Sohag university, Sohag, Egypt.
4pediatric department, Faculty of medicine, sohag university, Sohag, Egypt
Abstract
Introduction: Severity of illness (SOI) scores have been developed to predict the outcome and to provide a better quality of care with available resources.

Objective of the study: was to evaluate the predictive ability of Pediatric index of mortality-2 (PIM-2), pediatric index of mortality-3(PIM-3) and Pediatric risk of mortality IV (PRISM IV) in a resource-limited PICU.

Materials and methods: We conducted a prospective cohort study in PICU in Sohag University Hospital in the period from March 2018 to June 2020. We recorded the baseline patient characteristics, admission diagnoses, variables of PIM-2, PIM-3 and PRISM IV models and outcomes of children admitted to the PICU. We utilized Area Under Receiver Operating Characteristics (AU-ROC) curves and Goodness-of-fit (GOF) test to evaluate the discrimination and calibration of the three models.

Results: Of 451 patients enrolled, 171 (37.9%) died. Sepsis was the major admission diagnosis. The discrimination was acceptable for PRISM IV, while it was poor for both PIM-2 and PIM-3 as indicated by the AU-ROC which was (0.74; 95%CI: 0.62- 0.86 for PRISM IV) vs (0.69; 95% CI: 0.58- 0.81 for PIM-2) and (0.69; 95% CI: 0.57-0.81for PIM-3) (p < 0.0001). The calibration was poor for all scores as the p-value of GOF test for was < 0.0001 for all scores.

Conclusion: The discrimination of PRISM IV was acceptable and the best among the three models. All scores had poor calibration and under-predict mortality in our setting. We suggest utilizing them as quality indicators rather than in mortality prediction.
Keywords
Severity of illness assessment scores; discrimination; calibration
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