The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning
Mohamed, S., Hasb Elnabi, M., Moussa, M., Tawfik, H., Adly, M. (2019). The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning. EKB Journal Management System, 33(2), 8-15. doi: 10.21608/ajfm.2019.30444
Soheir Mohamed; Marwa Hasb Elnabi; Mona Moussa; Hany Tawfik; Mohamed Adly. "The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning". EKB Journal Management System, 33, 2, 2019, 8-15. doi: 10.21608/ajfm.2019.30444
Mohamed, S., Hasb Elnabi, M., Moussa, M., Tawfik, H., Adly, M. (2019). 'The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning', EKB Journal Management System, 33(2), pp. 8-15. doi: 10.21608/ajfm.2019.30444
Mohamed, S., Hasb Elnabi, M., Moussa, M., Tawfik, H., Adly, M. The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning. EKB Journal Management System, 2019; 33(2): 8-15. doi: 10.21608/ajfm.2019.30444

The Accuracy Comparison of Scoring Systems in the Outcome Prediction of Acute Organophosphate Poisoning

Ain Shams Journal of Forensic Medicine and Clinical Toxicology
Article 2, Volume 33, Issue 2, July 2019, Page 8-15  XML PDF (1.26 MB)
Document Type: Original Article
DOI: 10.21608/ajfm.2019.30444
View on SCiNiTO View on SCiNiTO
Authors
Soheir Mohamed1; Marwa Hasb Elnabi2; Mona Moussa3; Hany Tawfik4; Mohamed Adly5
1Forensic Medicine & Clinical Toxicology department, Faculty of Medicine, Sohag University,Egypt.
2Forensic Medicine & Clinical Toxicology department, Faculty of Medicine, Sohag University.
3Forensic Medicine & Clinical Toxicology department, Faculty of Medicine, Ain Shams University.
4Poison Control Center, Hospitals of Ain Shams University.
5Forensic Medicine & Clinical Toxicology department, Faculty of Medicine, Cairo University,Egypt.
Abstract
 




 Background: Organophosphates (OP) with high morbidity and mortality are one of the most common causes of poisoning especially in developing countries. Early diagnosis and appropriate treatment is often life saving as mortality rate of OP poisoning is still high. The objective of this study is to compare the accuracy of scoring systems (the sequential organ failure assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II) score and glasgow coma scale (GCS)) in the prediction of mortality of acute organophosphate poisoning. 
Methodology: A retrospective and prospective study was done on 200 patients with acute OP poisoning admitted to the Poison Control Center (PCC), hospitals of Ain Shams University in the period between 1/1/2016 and 31/12/2016. Information was collected from the sheets and computerized data base of the patients. SOFA score, APACHE II score and GCS were calculated to each patient admitted. The results were revised, coded and organized for statistical analysis. 
Results: The study results revealed 180 (90%) patients recovered and 20 (10%) patients died. The area under the curve of receiver operator characteristic (ROC) of SOFA score was 0.995, for APACHE II score was 0.986 and compared to GCS was 0.977 with significantly higher SOFA and APACHE II scores in the died patients than in the recovered patients (P <0.001). As regards GCS there was statistically significant difference between recovered and died patients (P <0.001). 
Conclusion: It could be concluded that SOFA score, APACHE II score and GCS systems can be used to predict mortality of acute organophosphate poisoning with preference to SOFA score which had the highest accuracy and predictive ability. From the previous results, our study recommends that application of SOFA score, APACHEII score and GCS are good predictors of high mortality in OP intoxicated patients which helps in proper allocation of resources particularly for intensive care unit patients. 
Keywords
Organophosphate; APACHE II score; SOFA score; Glasgow
Statistics
Article View: 619
PDF Download: 625