Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.
SY, E., Atakla, H., MBAYE, M., THIOUB, M., DOUMBIA, N., NDIAYE, P., KEBE, A., THIAM, A., BA, M. (2023). Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.. EKB Journal Management System, 18(1), 69-71. doi: 10.21608/pajn.2023.190195.1087
Elhadji Cheikh Ndiaye SY; Hugues Ghislain Atakla; Maguette MBAYE; Mbaye THIOUB; Nantenin DOUMBIA; Pape Sandène NDIAYE; Adja Aissatou KEBE; Alioune Badara THIAM; Momar Code BA. "Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.". EKB Journal Management System, 18, 1, 2023, 69-71. doi: 10.21608/pajn.2023.190195.1087
SY, E., Atakla, H., MBAYE, M., THIOUB, M., DOUMBIA, N., NDIAYE, P., KEBE, A., THIAM, A., BA, M. (2023). 'Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.', EKB Journal Management System, 18(1), pp. 69-71. doi: 10.21608/pajn.2023.190195.1087
SY, E., Atakla, H., MBAYE, M., THIOUB, M., DOUMBIA, N., NDIAYE, P., KEBE, A., THIAM, A., BA, M. Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.. EKB Journal Management System, 2023; 18(1): 69-71. doi: 10.21608/pajn.2023.190195.1087

Pregabalin and mecobalamin combination in the management of refractory neuropathic pain: a potential alternative to early surgery in disco-radicular conflicts.

Pan Arab Journal of Neurosurgery
Article 11, Volume 18, Issue 1, June 2023, Page 69-71  XML PDF (778.83 K)
Document Type: Original Articles
DOI: 10.21608/pajn.2023.190195.1087
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Authors
Elhadji Cheikh Ndiaye SY; Hugues Ghislain Atakla email orcid ; Maguette MBAYE; Mbaye THIOUB; Nantenin DOUMBIA; Pape Sandène NDIAYE; Adja Aissatou KEBE; Alioune Badara THIAM; Momar Code BA
Neurosurgery Department, Fann’s national teaching hospital, Dakar, Senegal, BP: 5035.
Abstract
Context and Objective: Neuropathic pain is pain resulting from injury to the nervous system. They are said to be peripheral when they are consecutive to a lesion of the peripheral nervous system and can concern a plexus, a root or a truncular attack. The aim of this study is to establish the interest of a combination of Pregabalin and Mechobalamin in the medical management of refractory neuropathic pain in the pre-operative period, and to highlight its advantages.
Patients and methods: This is a cross-sectional analytical study with a duration of 12 months from 30 September 2021 to 30 September 2022. Patients were divided into 2 groups: Pregabalin for group A and Pregabalin + Mecobalamin for group B. Patients who did not receive Pregabalin or Pregabalin + Mecobalamin were not included. Anonymity and confidentiality were preserved. Data were entered into Epi-Info 7.1.4.0 and analysed in STATA/SE 11.2.
Results: In 81.82% of the patients in group A, an indication for surgery was given after three (3) months of evolution against 18.18% of group B in whom surgery was performed after three (3) months of evolution.
Conclusion: This study shows that the fixed combination of pregabalin and mecobalamin gives the neurosurgeon time to prepare the operation. Its "minimal effective dose" power preserves the patient from intoxication and dependence.
Keywords
Neuropathic pain; Pregabalin; Mecobalamin; alternative; surgery
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