Biochemical effect of alpha –lipoic acid on oxidative stress and dysfunction in experimentally induced myocardial infarction | ||||
Scientific Journal of October 6 University | ||||
Article 4, Volume 4, Issue 1, July 2017, Page 27-35 PDF (317.86 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/sjou.2017.30463 | ||||
View on SCiNiTO | ||||
Authors | ||||
Hussein A. El Maksoud1; Usama E. Mahrous2; Ali H. El-far3; Kadry M. Sadek3; Al-Hossain H. Ali Ajaj4 | ||||
1Biochemistry Department, Faculty of Vet. Med. Moshtohor, Benha University, Egypt | ||||
2Biochemistry Department, Faculty of Vet. Med. Moshtohor, Benha University, Egypt. | ||||
3Animal and Poultry Behavior, Faculty of Vet. Med. Damnhour University, Egypt | ||||
4Lectuerer of Biochemisry, Faculty of Vet. Med. Damnhour University, Egypt. | ||||
Abstract | ||||
The present study was designed to evaluate the protective effect and treatment effect of Alpha lipoic acid administration on cardiac necrosis markers, some electrolytes and cardiac tissue antioxidants in myocardial necrosis induced experimentally in rats- The investigated serum and cardiac biochemical parameters were: A) Serum levels of creatine kinase (CK) ,creatine kinase MB (CK-MB), lactate dehydrogenase (LDH), aspartate aminotransferase (AST), total protein (T.P), albumin (Alb), glucose, calcium (Ca), sodium (Na), potassium (K), phosphorus (P). B) RBCs glucose 6 phosphate dehydrogenase (G-6-PDH). C) Cardiac antioxidants (SOD and CAT) and cardiac oxidant (MDA). | ||||
Keywords | ||||
Alpha – Lipoic Acid; Oxidative Stress; Myocardial Infarction and calcium | ||||
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