Clinical, Neuroimaging and Electroencephalographic Characteristics of Pediatric Medically Intractable Epilepsy | ||||
| Benha Journal of Applied Sciences | ||||
| Article 19, Volume 8, Issue 1, January 2023, Page 123-125 PDF (224.26 K) | ||||
| Document Type: Original Research Papers | ||||
| DOI: 10.21608/bjas.2023.211164.1170 | ||||
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| Authors | ||||
Wesam Elmenshawy Afifi1; Elham Abdelghafar Nawar2; Aziza Ibrahim Ali  3; Omima Mohamed Abdel Haie4; Aliaa Mohamed Elhady1
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| 1Lecturer of Pediatrics Faculty of Medicine - Benha University | ||||
| 2Professor of Pediatrics Faculty of Medicine - Benha University | ||||
| 3Department of Pediatrics Faculty of Medicine - Benha University | ||||
| 4Assistant Professor of Pediatrics Faculty of Medicine - Benha University | ||||
| Abstract | ||||
| Objectives: to investigate the clinical, neuroimaging, and electroencephalographic characteristics of pediatric medically intractable epilepsy in order to predict and overcome this intractability. Methods: We conducted a prospective case-control study with 50 participants, divided into a study group of 25 patients with refractory epilepsy and a control group of 25 epileptic children with good control of seizures. All participants underwent a comprehensive assessment, including medical history, physical examination, neuroimaging, neurophysiological evaluation, and metabolic workup. Results: The study revealed that total number of patients was 50 (25 case 12 male & 13 female and 25 control 11 male & 14 female). Children with refractory epilepsy had abnormal neuroimaging. Additionally, the interictal EEG monitoring showed more frequent epileptiform discharges in the refractory group. Conclusions: It is important to evaluate pediatric patients with medically intractable epilepsy. Abnormal development, neuroimaging and frequent epileptiform discharges on EEG may indicate a higher likelihood of refractory epilepsy for further research with large number. | ||||
| Keywords | ||||
| Clinical; Neuroimaging; Electroencephalographic; Epilepsy; Medically Intractable | ||||
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