Efficacy of Autologous Platelet-Rich Fibrin in Myringoplasty in Dogs | ||||
| Suez Canal University Medical Journal | ||||
| Article 9, Volume 26, Issue 4, April 2023, Page 0-0 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/scumj.2023.306444 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Samy M. El-Sayed* ; Nagy M. Iskander; Diaa ElDin M. ElHennawi; Yasser T. Madian; Alaa M. Farid | ||||
| Department of Otorhinolaryngology, Faculty of Medicine, Suez Canal University, Egypt | ||||
| Abstract | ||||
| Objective: To assess the effect of local application of platelet-rich fibrin in myringoplasty for perforated dogs’ tympanic membranes. Material and Methods: forty-four dogs were subjected to large central tympanic perforation (at least two quadrants) in the right ears and followed up for 8 weeks and further were divided into two equal groups randomly by lottery. Group (A): study group: PRF has been used in repairing dry chronic tympanic perforation in dogs in their right ears. Group (B): control group: PRF was not used only trimming of the edges of tympanic membrane perforation. Closure of the perforated tympanic membrane with platelet-rich fibrin membrane was assessed by healing. Results:The percentage of healing in the study group was 47.5% versus 25% in the control group. There were statistically significant differences between the Study Group and the Control Group regarding Healing at 8 weeks. The percentage of healing in the study group was 90% versus 75% in the control group. Conclusion: PRF membrane could be used successfully in the repair of tympanic membrane perforation and wound healing. This method could be more frequently preferred in the future in various areas as it is an autogenous material that is safe and effective, easy to use, and has low costs, while it does not prolong operating time. | ||||
| Keywords | ||||
| Myringoplasty; perforated tympanic membrane; PRF | ||||
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