Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children
Ali, A., Abdel Wahab, A., Gad, S., Nassar, S. (2023). Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children. EKB Journal Management System, 26(5), 0-0. doi: 10.21608/scumj.2023.306940
Ahmed A. Ali; Amina M. Abdel Wahab; Suzan S. Gad; Sanaa S. Nassar. "Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children". EKB Journal Management System, 26, 5, 2023, 0-0. doi: 10.21608/scumj.2023.306940
Ali, A., Abdel Wahab, A., Gad, S., Nassar, S. (2023). 'Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children', EKB Journal Management System, 26(5), pp. 0-0. doi: 10.21608/scumj.2023.306940
Ali, A., Abdel Wahab, A., Gad, S., Nassar, S. Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children. EKB Journal Management System, 2023; 26(5): 0-0. doi: 10.21608/scumj.2023.306940

Serum Chemerin as a Marker for Early Detection of Metabolic Syndrome in Obese Children

Suez Canal University Medical Journal
Article 7, Volume 26, Issue 5, May 2023, Page 0-0  XML
Document Type: Original Article
DOI: 10.21608/scumj.2023.306940
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Authors
Ahmed A. Ali* 1; Amina M. Abdel Wahab2; Suzan S. Gad2; Sanaa S. Nassar2
1Department of Pediatrics, El Ibrahimiya central hospital, Sharqia, Egypt
2Department of Pediatrics, Faculty of Medicine, Suez Canal University, Egypt
Abstract
Background: Chronic inflammatory conditions include metabolic syndrome (MetS), one of the most important worldwide health concerns. Chemerin, an adipokine, is involved in the relationship between MetS and inflammation. Aim: The goal of our research was to assess if serum chemerin might be used as a marker for early diagnosis of metabolic syndrome. Methods: The study included 42 obese and 42 non-obese healthy children and adolescents ranging in age from 5 to 17 years old. The subjects' anthropometric and blood pressure measurements were taken. The following data were collected: fasting blood glucose, serum triglycerides (TG), total cholesterol, high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c). The level of chemerin was measured using ELISA. Results: Serum chemerin levels were substantially greater in MetS obese than in non-MetS obese and healthy subjects (1211.71569 ng/ml versus 337.534.8 ng/ml and 470.3475.8 ng/ml, respectively, p0.001). By using correlation and multiple linear regression analysis, serum chemerin levels were found to be significantly correlated to impaired fasting blood sugar (r= 0.398, p = 0.009) and poor HDL (r= -0.386, p = 0.012). Conclusion: Chemerin levels in the blood have been linked to metabolic syndrome and could be used as an independent diagnostic marker for the condition.
 
Keywords
Children; metabolic syndrome; chemerin; obesity
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