Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?
Habba, E., Elgebaly, F., Abdel-Hafiz, A., Elwy, D., Mansour, S. (2023). Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?. EKB Journal Management System, 6(1), 53-59. doi: 10.21608/ajgh.2023.216455.1034
Eslam Ahmed Habba; Fatma Ali Elgebaly; Ahmed Abdel-Hafiz; Doaa Elwy; Shimaa Moustafa Mansour. "Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?". EKB Journal Management System, 6, 1, 2023, 53-59. doi: 10.21608/ajgh.2023.216455.1034
Habba, E., Elgebaly, F., Abdel-Hafiz, A., Elwy, D., Mansour, S. (2023). 'Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?', EKB Journal Management System, 6(1), pp. 53-59. doi: 10.21608/ajgh.2023.216455.1034
Habba, E., Elgebaly, F., Abdel-Hafiz, A., Elwy, D., Mansour, S. Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?. EKB Journal Management System, 2023; 6(1): 53-59. doi: 10.21608/ajgh.2023.216455.1034

Helicobacter Pylori And Non-alcoholic Fatty Liver Disease Is There A Relationship?

African Journal of Gastroenterology and Hepatology
Volume 6, Issue 1, 2023, Page 53-59  XML PDF (486.39 K)
Document Type: Original Clinical
DOI: 10.21608/ajgh.2023.216455.1034
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Authors
Eslam Ahmed Habba1; Fatma Ali Elgebalyorcid 2; Ahmed Abdel-Hafiz3; Doaa Elwy4; Shimaa Moustafa Mansour email orcid 2
1Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University.
2Department of Tropical Medicine and Infectious Diseases, Faculty of Medicine, Tanta University
3Emergency Medicine and Intensive Care Specialist Nuremberg Hospital, Paracelsus Medical Private University
4Department of public health, Faculty of medicine, Tanta University, Egypt
Abstract
Background and Aim: researchers proposed a connection between H pylori and obesity, diabetes, and improper lipid metabolism. The studies have discovered that H pylori infection is one of the elements for Non-Alcoholic Fatty liver Disease (NAFLD) to progress and that getting rid of Helicobacter pylori (H pylori) can partially stop the evolution of NAFLD. Other research, however, argues that there is no definitive link between H pylori infection and NAFLD. We aimed to investigate the prevalence of H pylori infection in NAFLD.
Materials and Methods: This study was conducted on 110 patients diagnosed with NAFLD by ultrasound and fibroscan. They were assessed for the diagnosis of H. pylori infection by H. pylori antigen in stool.
Results: The patients were classified into H pylori +ve group and H pylori -ve group. There was a significant difference between both groups regarding sex (p = 0.01) and diabetes mellitus (p = 0.000) and no significant difference between both groups as regard smoking, hypertension, and BMI. There was significant difference between both groups regarding steatosis (p = 0.0001) and fibrosis grade (p = 0.0001)
Conclusion: the prevalence of H. Pylori has increased in NAFLD; also, H. pylori may be an independent risk factor for NAFLD.
Keywords
H.pylori; PPI; BMI; HDL; LDL
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