Chitosan-Silver Nanoparticles: A Versatile Conjugate for Biotechnological Advancements | ||||
| Journal of Advanced Pharmacy Research | ||||
| Article 4, Volume 7, Issue 3, July 2023, Page 163-169 PDF (228.52 K) | ||||
| Document Type: Review Article | ||||
| DOI: 10.21608/aprh.2023.218891.1222 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Shaimaa Faisal1; Ahmed A Hamed2; Riham Shawky3; Mohamed Emara   3
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| 1Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University Egyptian Drug Authority (EDA), Cairo 15301, Egypt | ||||
| 2Department of Microbial Chemistry, Genetic Engineering and Biotechnology Research Division, National Research Centre, Giza, Egypt | ||||
| 3Department of Microbiology and Immunology, Faculty of Pharmacy, Helwan University, Ain Helwan 11795, Cairo, Egypt. | ||||
| Abstract | ||||
| Nano technology has emerged as a powerful field that enables the manipulation and control of matter at the nanoscale. One particular area of interest is the synthesis and application of silver nanoparticles (AgNPs) conjugated with chitosan, a biocompatible and biodegradable polysaccharide. This conjugate offers unique opportunities for various industries, particularly in biomedicine and environmental remediation. In the biomedical field, chitosan-silver nanoparticle conjugates exhibit significant potential as antimicrobial agents, wound dressings, and drug delivery systems. The combination of chitosan's biocompatibility and silver nanoparticles' antimicrobial activity provides an effective approach to combat infections and promote wound healing. Furthermore, the chitosan matrix can facilitate controlled release of therapeutic agents, enhancing their efficacy and reducing potential side effects. In environmental applications, chitosan-silver nanoparticle conjugates show promise for water purification, as they can effectively remove pollutants and disinfect water due to the antimicrobial properties of silver nanoparticles. Chitosan's ability to form gels and membranes further facilitates their use in filtration systems for wastewater treatment and environmental remediation. In conclusion, the conjugation of chitosan with silver nanoparticles represents a promising avenue in nano technology. This conjugate offers versatile applications in biomedicine and environmental remediation, leveraging the synergistic properties of both components. Further research and development are required to optimize the synthesis techniques, understand the mechanisms of action, and assess the long-term effects to ensure safe and effective utilization of chitosan-silver nanoparticle conjugates in various industries. | ||||
| Keywords | ||||
| Chitosan; Nanoparticles; Conjugate; Biotechnology; antimicrobial | ||||
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