Comparison between Sesame Oil and Glycyrrhizaglabra Effect as Phytoestrogen on Male Albino Rats | ||||
The Egyptian Journal of Hospital Medicine | ||||
Article 3, Volume 75, Issue 4, April 2019, Page 2550-2555 PDF (408.42 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/ejhm.2019.31084 | ||||
View on SCiNiTO | ||||
Authors | ||||
Eman G.E. Helal 1; Mohamed A. El-Aleem2; Shaimaa S. Ahmed1 | ||||
1Zoology Department, Faculty of Science, Al-Azhar University (Girls), Cairo, Egypt | ||||
2Physiology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
Background: Phytoestrogen is a plant-derived compound, which has estrogenic effect and it is found in liquorice root extract and sesame oil.Aim of the work:To investigate some biochemical effects of liquorice root extract and sesame oil on male albino rats. Materials and methods: 18 animals were divided randomly into three groups. Group A: Control group, group B: rats treated with oral dose of liquorice10 mg/kg body weight/day for one month, andgroup C: rats treated with oral dose of sesame oil 1 ml/kg body weight/day. At the end of the experiment, blood samples were collected for biochemical analysis. Results: Liquorice and sesame oil induced highly significant decrease in TC, TG, LDL, VLDL, LDL/HDL(p<0.01)and significant increase in HDL(p<0.05). They also showedhighly significantly decrease in FSH, testosterone and sperm countcompared to control group(p<0.01). Conclusion:The study supports that the high level intake of liquoriceroot extract orsesame oil caused hormonal disturbance and decreases sperm count. | ||||
Keywords | ||||
Liquorice root; Sesame oil; Lipid profile; albino rats; physiological parameters | ||||
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