Effect of combination between serratus anterior plane block and transversus thoracis plane block on the management of acute postmastectomy pain: a prospective randomized clinical trial Sh | ||||
| SECI Oncology Journal | ||||
| Volume 11, Issue 3, July 2023, Page 212-221 | ||||
 View on SCiNiTO | ||||
| Abstract | ||||
| Background: The serratus anterior plane (SAP) block cannot block the most internal mammary region, whereas, the transversus thoracis plane (TTP) block can. Hence, we studied patients undergoing mastectomy to determine whether the combination of these two blocks provides better pain control than the serratus anterior plane block alone. Methods: Fifty-four adult female patients scheduled for modified radical mastectomy were randomly allocated to one of two groups. Group (A) (n = 27) received the serratus anterior plane block alone, and group (B) (n = 27) received the transversus thoracis plane block combined with the serratus anterior plane block. The primary outcome measure was post-operative opioid consumption. Secondary outcome measures were visual analogue scale (VAS), duration till request of the first analgesia, and total sum of intra-operative fentanyl consumption. Results: the cumulative 24-hour postoperative opioid consumption, VAS score both at rest and movement, time of request of the first analgesia, and intraoperative fentanyl consumption showed no significant difference between the two groups. Conclusion: The combination of transversus thoracis plane block and serratus anterior plane block has no additional analgesic effect than serratus anterior plane block alone for the management of acute postmastectomy pain. Clinical trial registration: registered at “www.clinicaltrial.gov” under number: (NCT04375111). | ||||
| Keywords | ||||
| breast cancer; mastectomy; analgesia; regional block; serratus anterior plane block; transversus thoracis plane block | ||||
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