Neuroglobin as a biomarker in children with autism spectrum disorder. | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 06 August 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2023.219755.1452 | ||||
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| Authors | ||||
Aya Ahmed Mohamed  1; Samir Mohammed Mounir2; Ahmed Abdelfadil Saedii3; Yossra Samir Fadle4
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| 1Resident at pediatric and neonatology department, faculty of Medicine, Minia University, Egypt | ||||
| 2Assistant Professor of pediatrics, Faculty of Medicine, Minia University, Egypt | ||||
| 3Assistant Professor of clinical pathology Faculty of Medicine, Minia University, Egypt | ||||
| 4Lecturer of pediatrics, Faculty of Medicine, Minia University, Egypt | ||||
| Abstract | ||||
| Neuroglobin as a biomarker in children with autism spectrum disorder. Abstract: Background: Autism spectrum disorder (ASD) is a group of neurodevelopmental conditions diagnosed based on behavioral assessments that reveal deficits in social interactions. Objectives: The aim of this study is to investigate the possible role of neuroglobin as a biomarker in children with ASD. Methods: This cross-sectional study was carried out at Minia University of Children, Obstetrics and Gynecology Hospital over the period from January 2022 to January 2023. It was conducted on 19 children diagnosed with ASD attending to the Pediatric neuropsychiatry out-patient clinic or admitted to the pediatric neurology inpatient ward of Minia University of Children, Obstetrics and Gynecology Hospital during the period of the study. They were subdivided into two groups: Group I (N=19): included autistic children (14 males & 5 females) for fulfillment the criteria of autism. Group II (N=30): included apparently healthy children (21 females & 9 males) whose age and sex were matched with group I. The two groups were subjected to careful detailed history taking, complete clinical examination, and laboratory investigations including: complete blood count, Serum Neuroglobin level. Results: Our results show that there were statistically significant differences as regard serum neuroglobin level between group (I), group (II). Conclusion: In conclusion, higher serum neuroglobin levels among children with ASD than controls. | ||||
| Keywords | ||||
| Keywords: ASD; children; neuroglobin; controls | ||||
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