Possible ameliorative effect of dietary curcumin against water copper toxicity in Clarias gariepinus fish | ||||
| Egyptian Journal of Aquatic Biology and Fisheries | ||||
| Article 52, Volume 27, Issue 4, July and August 2023, Page 825-845 PDF (516.04 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejabf.2023.313124 | ||||
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| Author | ||||
| Khalid H. Zaghloul et al. | ||||
| Abstract | ||||
| A total of seventy-two healthy Nile catfish; Clarias gariepinus were distributed into four distinct groups. These groups were fed either a commercial basal diet or a diet enriched with 500 mg curcumin/kg ration for 12 weeks. Among these groups, two groups were exposed to a sublethal concentration of copper (0.35 mg/l) and were fed a normal diet or a curcumin-enriched diet as an antioxidant. The other two control groups were comprised of fish raised in dechlorinated tap water and were fed either the commercial basal diet or the curcumin-supplemented diet for the same 12-week experimental period. The study’s findings revealed that Clarias gariepinus, when subjected to a sublethal copper concentration (0.35 mg/l), accumulated a greater amount of copper in their vital organs (gills, liver, and muscles) after 12 weeks. This accumulation coincided with a decrease in fish’s rate of growth and quality of meat (indicated by higher muscle water content and ash but lower muscle total protein and lipids), a reduction in RBCs count, Hb content, and Ht values, and an increase in WBCs count, serum glucose, creatinine, uric acid, total protein, albumin, globulin levels, A/G ratio, and AST, ALT and ALP activities when compared to the control group of fish with a highly significant difference (P < 0.01). However, fish that were exposed to copper toxicity and fed curcumin supplemented diet (500 mg/kg diet) exhibited values that were more or less similar to those of the control group of fish that were reared in dechlorinated tap water and fed a commercial basal diet or curcumin supplemented basal diet (500mg/kg diet). | ||||
| Keywords | ||||
| Copper toxicity; Clarias gariepinus; Growth indices; Physiological status; Antioxidant Curcumin supplementation | ||||
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