Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats
F.Y., E., M., E., M., S., A., A. (2016). Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats. EKB Journal Management System, 30(1), 29-38. doi: 10.21608/bvmj.2016.31341
El-Regily A. F.Y.; El-Hindawy U. M.; Sadek K. M.; Abd El-Maksoud H.A. A.. "Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats". EKB Journal Management System, 30, 1, 2016, 29-38. doi: 10.21608/bvmj.2016.31341
F.Y., E., M., E., M., S., A., A. (2016). 'Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats', EKB Journal Management System, 30(1), pp. 29-38. doi: 10.21608/bvmj.2016.31341
F.Y., E., M., E., M., S., A., A. Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats. EKB Journal Management System, 2016; 30(1): 29-38. doi: 10.21608/bvmj.2016.31341

Biochemical alterations of inflammatory markers in experimentally induced diabetes in rats

Benha Veterinary Medical Journal
Article 4, Volume 30, Issue 1, March 2016, Page 29-38  XML PDF (271.77 K)
Document Type: Original Article
DOI: 10.21608/bvmj.2016.31341
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Authors
El-Regily A. F.Y.1; El-Hindawy U. M.1; Sadek K. M.1; Abd El-Maksoud H.A. A.2
1Department of Biochemistry, Faculty of Veterinary Medicine, Damanhour University
2Department of Biochemistry, Faculty of Veterinary Medicine, Benha University
Abstract
This study was evaluated the protecting effect of rutin on the glycemic condition, lipid profile, in
streptozotocin (STZ)-induced experimental diabetic in rats. With respect to an orally administrated rutin
on serum glucose, the result is showing a significant decrease in glucose concentration when compared
to diabetic group, While, a significant increase in insulin concentration when compared to diabetic.
Moreover, the results revealed that, an administration of streptozotocin (STZ) showing significant
increase in triacylglycerol, total cholesterol, LDL-c and VLDL-C concentration when compared with
control group, while, showing significant decrease in HDL-C concentration and serum AST and ALT
activity when compared to the control group. The data revealed also significant increase in serum LMDA
concentration. While, significant decrease in serum calcium concentration when compared to the
control group
Keywords
streptozotocin; Rutin; glucose; Insulin; L-MDA; calcium
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