Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks
Mahfouz, M., Zyan, K., Abdel-Hamid, H. (2016). Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks. EKB Journal Management System, 30(1), 39-50. doi: 10.21608/bvmj.2016.31342
Mohamed K. Mahfouz; Kamel A. M. Zyan; Hossam H. Abdel-Hamid. "Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks". EKB Journal Management System, 30, 1, 2016, 39-50. doi: 10.21608/bvmj.2016.31342
Mahfouz, M., Zyan, K., Abdel-Hamid, H. (2016). 'Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks', EKB Journal Management System, 30(1), pp. 39-50. doi: 10.21608/bvmj.2016.31342
Mahfouz, M., Zyan, K., Abdel-Hamid, H. Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks. EKB Journal Management System, 2016; 30(1): 39-50. doi: 10.21608/bvmj.2016.31342

Biochemical effect of β-hydroxy-β-methylbutyrate calcium and creatine supplementations on some blood parameters, pro-inflammatory cytokines and growth performance of broiler chicks

Benha Veterinary Medical Journal
Article 5, Volume 30, Issue 1, March 2016, Page 39-50  XML PDF (344.65 K)
Document Type: Original Article
DOI: 10.21608/bvmj.2016.31342
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Authors
Mohamed K. Mahfouz1; Kamel A. M. Zyan2; Hossam H. Abdel-Hamid1
1Department of Biochemistry, Faculty of Veterinary Medicine, Benha University, Egypt
2Department of Poultry Diseases, Faculty of Veterinary Medicine, Benha University, Egypt
Abstract
One hundred and sixty-five one-day old Cobb broiler chicks were allocated into 3 groups to investigate the
effect of dietary 0.1% β-hydroxy- β-methylbutyrate calcium (HMB) and 0.1% creatine on some blood
parameters, pro-inflammatory cytokines and growth performance parameters in terms of total feed intake
(TFI), total body weight gain (TBWG), total body weight and feed conversion ratio (FCR) during certain
time intervals (21st day and 42nd day) versus control group (0 treatment). Some biochemical changes were
recorded at the 42nd day among creatine supplemented group in the form of significantly high results of both
triglycerides and T3 in group 3 (creatine) than that of the control group on the same day at P value > 0.05.
HMB supplemented group showed significantly lower results of ALT (mean) than that of control group at
(P value > 0.05) on the 21st day which became insignificant at the 42nd day. Dietary 0.1% HMB-Ca recorded
better growth performance parameters in terms of TFI (4.527), TBWG (2.515), TBW (2.555) and TFCR
(1.8) if compared to creatine supplemented group of (4.664, 2.508, 2.549 and 1.86) respectively and the
control group of TFI equaled to 4.7432, TBWG equaled to 2.156, TBW equaled to 2.1987 and TFCR
equaled to 2.2 at the end of the experiment. HMB and creatine supplementations had no effect on other
blood parameters, viz. AST, urea, creatinine, total protein, FFA, T4, T3/T4 ratio, TSH, uric acid, cholesterol,
HDL and LDL, and pro-inflammatory cytokines namely IL-6, IL-2 and TNF-α.
Keywords
HMB-Ca; Creatine; broiler chicks; TFI; FCR; TBWG; TBW
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