Review on different analytical techniques for analysis of atenolol alone or in combination with other antihypertensive drugs in different matrices | ||||
| ERU Research Journal | ||||
| Volume 2, Issue 4, October 2023, Page 648-681 PDF (379.29 K) | ||||
| Document Type: Review articles | ||||
| DOI: 10.21608/erurj.2023.212635.1030 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Omar M El-Abassy ; Israa Mamdouh Nour  ; Mohamed Badrawy
| ||||
| Pharmaceutical Chemistry Department, Faculty of Pharmacy, Egyptian Russian University, Badr City, 11829, Cairo, Egypt. | ||||
| Abstract | ||||
| Several analytical techniques were reported for the analysis of atenolol (antihypertensive) either in pharmaceutical dosage forms or in biological samples by various analytical techniques including HPLC, spectrophotometry, fluorimetry, and electrochemical methods. This article includes important information about the cited drug involving physical and chemical characteristics in addition to its pharmacological actions. Atenolol is a β-adrenoreceptor blocker that is used for hypertension, myocardial infarction, and angina. It works via inhibition of renin release, angiotensin -II, and aldosterone production. Atenolol is combined with several antihypertensive agents like losartan, amlodipine, and nifedipine. This review is concerned with different analytical methods of atenolol either alone or with others. The most common method that is used for the analysis of the studied drug is the chromatographic technique then spectroscopy. Fluorimetric and electrochemical methods were used mostly for the determination of atenolol in biological fluids. All methods were validated according to ICH. | ||||
| Keywords | ||||
| Atenolol; Analytical methods; antihypertensive | ||||
|
Statistics Article View: 268 PDF Download: 265 |
||||
