Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules
Elsawy, M., Elhabashy, H., Soliman, M., Ahmed, A. (2019). Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules. EKB Journal Management System, 75(4), 2653-2660. doi: 10.21608/ejhm.2019.31456
Mohammed M. Elsawy; Hatem Salah Eldin Elhabashy; Marwa Abd ElMonem Soliman; Assem Ahmed Mohammed Ahmed. "Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules". EKB Journal Management System, 75, 4, 2019, 2653-2660. doi: 10.21608/ejhm.2019.31456
Elsawy, M., Elhabashy, H., Soliman, M., Ahmed, A. (2019). 'Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules', EKB Journal Management System, 75(4), pp. 2653-2660. doi: 10.21608/ejhm.2019.31456
Elsawy, M., Elhabashy, H., Soliman, M., Ahmed, A. Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules. EKB Journal Management System, 2019; 75(4): 2653-2660. doi: 10.21608/ejhm.2019.31456

Histopathological and Cytological Efficacy in The Diagnosis of Solitary Thyroid Nodules

The Egyptian Journal of Hospital Medicine
Article 18, Volume 75, Issue 4, April 2019, Page 2653-2660  XML PDF (702.59 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.31456
View on SCiNiTO View on SCiNiTO
Authors
Mohammed M. Elsawy1; Hatem Salah Eldin Elhabashy1; Marwa Abd ElMonem Soliman2; Assem Ahmed Mohammed Ahmed email 1
1Department of Otorhinolaryngology, Faculty of Medicine, Al-Azhar University
2Department of general Pathology, Faculty of Medicine, Al-Azhar University
Abstract
Background: thyroid nodules are found in 4-7% of the population, the preferred diagnostic approach is avoidance of numerous radiologic evaluations, and early performance fine-needle aspiration. Objectives: the aim of this study was to evaluate the efficacy of fine needle aspiration cytology (FNAC) and histopathological assessment in diagnosis of solitary thyroid nodules. Methods: this study was done on twenty patients diagnosed as solitary thyroid nodule. All the patients’ FNAC and histopathological results were reviewed, confirmed, correlated and evaluated. Results: there were 4(20%) men and 16(80%) women, with a male-to-female ratio of 1: 4. The patients studied ranged in age from 17 to 65 years, with the majority ranging in age between 25 and 40 years (30%). According to FNAC findings, 65% were benign/non-neoplastic and 35% were malignant aspirates. The most common benign lesion diagnosed by FNAC was a colloid nodule (25%), whereas the most common malignant lesion was papillary carcinoma (30%). There were no false-positive cases (0%). A false-negative result was found in only two cases (10%). According to the histopathological findings, 60% were benign/non-neoplastic lesions and 40% were malignant. The most common benign/non-neoplastic lesions were colloid goiter (25%) and follicular adenoma (15%), whereas the most common malignant lesion was papillary carcinoma (35%). Conclusion: FNAC is a useful diagnostic method, but it has some limitations in the diagnosis of subtypes of solitary thyroid nodules such as follicular lesion. Histopathological study provides a more accurate diagnosis and overcomes these limitations.
Keywords
Solitary thyroid nodule; Fine needle aspiration biopsy (FNAB); Fine needle aspiration cytology (FNAC); histopathology
Statistics
Article View: 269
PDF Download: 465