Diagnostic value of Multi Detector Computed Tomography in Assessment of Epicardial Adipose Tissue with Coronary Artery Disease

Refaat, Medhat; Abo Elezz, Mona Othman; Helmy, Ibrahim Mostafa; Helal, Ahmed Fathi Mohamed Ibrahim; El-shazly, Islam Mahmoud

doi:10.21608/bmfj.2023.224511.1859

	Diagnostic value of Multi Detector Computed Tomography in Assessment of Epicardial Adipose Tissue with Coronary Artery Disease
Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 26 August 2023 PDF (371.97 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2023.224511.1859
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Authors
Medhat Refaat¹; Mona Othman Abo Elezz¹; Ibrahim Mostafa Helmy¹; Ahmed Fathi Mohamed Ibrahim Helal ²; Islam Mahmoud El-shazly³
¹Professor of Radiodiagnosis, Faculty of Medicine, Benha University
²Department of Radiodiagnosis Faculty of Medicine- AinSham University
³Lecturer of Radiodiagnosis, Faculty of Medicine, Benha University
Abstract
Background: Current Multi Detector Computed Tomography (MDCT) systems allow the visualization of the entire heart volume during an entire heart cycle with high density resolution. MDCT imaging is thus opened to a wide spectrum of cardiac applications. This study aimed to evaluate out the diagnostic value of multi detector computed tomographic in assessment of epicardial adipose tissue with coronary artery disease. Methods: This Prospective, non-controlled nonrandomized study was conducted on 75 patients who underwent CT angiogram due to acute coronary syndrome occurrence. For further assessment of CAD patients divided into two groups: non-CAD group: 25 subjects with normal coronary arteries and CAD group: 50 subjects with coronary artery lesion. Results: This study included 75 patients; their mean age was 61.85 years. 61% of the studied subjects were males and 38% were females. ROC curve of EFV was conducted for prediction of CAD disease activity. EFV showed 0.813 area under curve at cut off level 60.39 with good sensitivity and specificity. ROC curve of Ca score was conducted for prediction of CAD disease activity. Ca score showed 0.947 area under curve at cut off level 90 with high sensitivity and specificity. Conclusion: The EAT volume has good prognostic value for developing CAD and increased EAT is considered a risk factor for CAD. Ca score could have an appropriate prognostic value for the determination of coronary artery disease.
Keywords
Diagnostic value; Multi Detector Computed Tomography; Epicardial Adipose Tissue; Coronary Artery Disease


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