Seroprevalence of cytomegalovirus infection among pregnant women attending some hospitals in Kaduna State, Nigeria

Aliyu, Muhammad Sani; Sani, Kauna; Hussaini, Ibrahim Mohammed; Tijani, Muhammad Bashir; Garba, Ibrahim; Doko, Muhammad Hassan Isa; Sulaiman, Mamunu Abdulkadir; Abdurrazaq, Maryam; Abdullahi, Murjanatu Muhammad; Sulaiman, Asmau Nna

doi:10.21608/mid.2023.222922.1578

	Seroprevalence of cytomegalovirus infection among pregnant women attending some hospitals in Kaduna State, Nigeria
Microbes and Infectious Diseases
Articles in Press, Accepted Manuscript, Available Online from 28 August 2023 PDF (775.29 K)
Document Type: Original Article
DOI: 10.21608/mid.2023.222922.1578
View on SCiNiTO
Authors
Muhammad Sani Aliyu¹; Kauna Sani¹; Ibrahim Mohammed Hussaini ¹; Muhammad Bashir Tijani¹; Ibrahim Garba²; Muhammad Hassan Isa Doko¹; Mamunu Abdulkadir Sulaiman¹; Maryam Abdurrazaq¹; Murjanatu Muhammad Abdullahi¹; Asmau Nna Sulaiman¹
¹Department of Microbiology, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria
²Department of Microbiology, Faculty of Science, Federal University, Gusau, Nigeria
Abstract
Background: Cytomegalovirus (CMV) infection especially in pregnancy may cause complications such as congenital infections leading to neurological disabilities in children that result in blindness, neuro-developmental delay, and sensory neural hearing loss. This study was carried out to determine the seroprevalence of cytomegalovirus infection among pregnant women attending antenatal clinics in Yusuf Dan Tsoho and 44 Nigerian Army Reference Hospitals in Kaduna metropolis. Materials and Methods: Blood samples were collected from ninety-two pregnant women and screened for CMV IgM antibodies using ELISA. Structured questionnaire was used to obtain data on socio-demographic and risk factors associated with the CMV infection. Results: Out of the 92 pregnant women examined, 30 (32.6%) tested positive to CMV IgM antibodies. There was statistically significant association between CMV infection and occupation, previous pregnancy and sharing of cups or utensils. There was no significant association between CMV infection and marital status, gestation age, history of blood transfusion, age and educational level. Conclusion: The high prevalence of CMV infection observed in this study indicates that the virus is prevalent in the study area, and it is therefore advisable that routine screening of CMV infection be implemented for all pregnant women in the State.
Keywords
Seroprevalence; Cytomegalovirus; IgM; Pregnant women; Kaduna


Statistics Article View: 174 PDF Download: 75