Quality of Life in Patients with Systemic Lupus Erythematosus | ||||
| Sohag Medical Journal | ||||
| Article 15, Volume 22, Issue 3, October 2018, Page 125-131 PDF (646.72 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/smj.2018.31607 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Aya M Ahmed1; Mohammed Ali Ismail2; Sahar AbdEL-Rahman Elsayed2; Rabab Hussein Ali1 | ||||
| 1Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University | ||||
| 2Department of Rheumatology and Rehabilitation, Faculty of Medicine, Sohag University | ||||
| Abstract | ||||
| Introduction: Systemic lupus erythematosus (SLE) is a chronic disease that results in variable and occasionally life-threatening manifestations. persons with SLE may experience a wide range of physical, psychological and social problems that affect quality of life. Aim of the work: Assess quality of life in the patients suffering from systemic lupus erythromatosus. Patients and Methods:The study was conducted on forty patients, with systemic lupus erythematosus [32 females (80%) and 8 males (20%)] and forty healthy adults of matched age and sex, as control group [30 female (80%) and 10 males (20%)]. The patients selected from the rheumatology outpatient clinic of Sohag University hospital. An informed written consent had been taken from all patients. Results: The increase in the disease activity, as assessed bysystemic lupus erythematosus disease activity index (SLEDAI) was significantly associated with more impaired quality of life as assessed by SF-36 and systemic lupus erythematosus quality of life questionnaire (SLEQOL). Conclusion:SLE patients have more significantly impaired quality of life, as assessed by short form-36(SF-36), and systemic lupus erythematosus quality of life questionnaire (SLEQOL) than the controls. | ||||
| Keywords | ||||
| SLE; quality of life | ||||
|
Supplementary Files
|
||||
| References | ||||
|
1. Megari K. Quality of Life in Chronic Disease Patients. Health psychology research. 2013;1(3):e27. 2. Tsokos GC. Systemic lupus erythematosus. The New England journal of medicine. 2011;365(22):2110-21. 3. Ware JE, Jr., Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical care. 1992;30(6):473-83. 4. Alarcon GS, McGwin G, Jr., Uribe A, Friedman AW, Roseman JM, Fessler BJ, et al. Systemic lupus erythematosus in a multiethnic lupus cohort (LUMINA). XVII. Predictors of self-reported health-related quality of life early in the disease course. Arthritis and rheumatism. 2004;51(3):465-74. 5. Doria A, Rinaldi S, Ermani M, Salaffi F, Iaccarino L, Ghirardello A, et al. Health-related quality of life in Italian patients with systemic lupus erythematosus. II. Role of clinical, immunological and psychological determinants. Rheumatology. 2004;43(12):1580-6. 6. Yilmaz-Oner S, Oner C, Dogukan FM, Moses TF, Demir K, Tekayev N, et al. Health-related quality of life assessed by LupusQoL questionnaire and SF-36 in Turkish patients with systemic lupus erythematosus. Clinical rheumatology. 2016;35(3):617-22. 7. Barnado A, Wheless L, Meyer AK, Gilkeson GS, Kamen DL. Quality of life in patients with systemic lupuserythematosus (SLE) compared with related controls within a unique African American population. Lupus. 2012;21(5):563-9. 8. Mok CC, Ho LY, Cheung MY, Yu KL, To CH. Effect of disease activity and damage on quality of life in patients with systemic lupus erythematosus: a 2-year prospective study. Scandinavian journal of rheumatology. 2009;38(2):121-7. 9. Chaigne B, Chizzolini C, Perneger T, Trendelenburg M, Huynh-Do U, Dayer E, et al. Impact of disease activity on health-related quality of life in systemiclupus erythematosus - a cross-sectional analysis of the Swiss Systemic Lupus Erythematosus Cohort Study (SSCS). BMC immunology. 2017;18(1):17. 10. Shen B, Feng G, Tang W, Huang X, Yan H, He Y, et al. The quality of life in Chinese patients with systemic lupus erythematosus is associated with disease activity and psychiatric disorders: a path analysis. Clinical and experimental rheumatology. 2014;32(1):101-7. 11. Khanna S, Pal H, Pandey RM, Handa R. The relationship between disease activity and quality oflife in systemic lupus erythematosus. Rheumatology. 2004;43(12):1536-40. 12. Freire EA, Bruscato A, Leite DR, Sousa TT, Ciconelli RM. Translation into Brazilian Portuguese, cultural adaptation and validatation of the systemic lupus erythematosus quality of life questionnaire (SLEQOL). Acta reumatologica portuguesa. 2010;35(3):334-9. 13. Leong KP, Kong KO, Thong BY, Koh ET, Lian TY, Teh CL, et al. Development and preliminary validation of a systemic lupus erythematosus-specific quality-of-life instrument (SLEQOL). Rheumatology. 2005;44(10):1267-76. 14. Kasitanon N, Wangkaew S, Puntana S, Sukitawut W, Leong KP, Tan Tock Seng Hospital Lupus Study G, et al. The reliability, validity and responsiveness of the Thai version of Systemic Lupus Erythematosus Quality of Life (SLEQOL-TH) instrument. Lupus. 2013;22(3):289-96. 15. Rinaldi S, Doria A, Salaffi F, Ermani M, Iaccarino L, Ghirardello A, et al. Health-related quality of life in Italian patients with systemic lupus erythematosus. I. Relationship between physical and mental dimension and impact of age. Rheumatology. 2004;43(12):1574-9. 16. Jolly M, Pickard SA, Mikolaitis RA, Rodby RA, Sequeira W, Block JA. LupusQoL-US benchmarks for US patients with systemic lupus erythematosus. The Journal of rheumatology. 2010, 37:1828–33.
| ||||
|
Statistics Article View: 440 PDF Download: 641 |
||||
