Preparation of rabies antiserum in tetanus immunized horses | ||||
| Benha Veterinary Medical Journal | ||||
| Article 17, Volume 29, Issue 2, December 2015, Page 147-152 PDF (266.71 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bvmj.2015.31686 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Attyat M. Kotb; Wafaa R. Abdel Aziz | ||||
| Veterinary Serum and Vaccine Research Institute; Abassia, Cairo | ||||
| Abstract | ||||
| The present work deals with the use of previously tetanus immunized horses for preparation of rabies antiserum in addition to investigate the effect of simultaneous immunization of horses against rabies and tetanus in order to prepare a bivalent anti-rabies and tetanus serum. The obtained results of applied serological tests revealed that the presence of tetanus antibodies in previously immunized horses did not affect the levels of induced rabies antibodies while simultaneous immunization resulted in high titers of rabies antibodies (256 IU/ml) as compared to such titers resulted in horses immunized with rabies vaccine alone (128 IU/ml). These findings suggest an enhancing action of tetanus antigen on antibody response against rabies and the prepared anti-serum can be used in emergency bite injuries in animals protecting them against both of rabies and tetanus infections as noticed in experimentally rabies infected mice. | ||||
| Keywords | ||||
| rabies; Tetanus; Antiserum; Anti- rabies; Horses | ||||
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