Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract
Zaatout, H., Ghareeb, D., Abd-Elgwad, A., Ismael, A. (2019). Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract. EKB Journal Management System, 3(2), 33-38. doi: 10.21608/rpbs.2019.12251.1032
Hala Zaatout; Doaa Ghareeb; Alshimaa Abd-Elgwad; Amany Ismael. "Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract". EKB Journal Management System, 3, 2, 2019, 33-38. doi: 10.21608/rpbs.2019.12251.1032
Zaatout, H., Ghareeb, D., Abd-Elgwad, A., Ismael, A. (2019). 'Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract', EKB Journal Management System, 3(2), pp. 33-38. doi: 10.21608/rpbs.2019.12251.1032
Zaatout, H., Ghareeb, D., Abd-Elgwad, A., Ismael, A. Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract. EKB Journal Management System, 2019; 3(2): 33-38. doi: 10.21608/rpbs.2019.12251.1032

Phytochemical, antioxidant, and anti-inflammatory screening of the Egyptian Ulva lactuca methanolic extract

Records of Pharmaceutical and Biomedical Sciences
Article 3, Volume 3, Issue 2, September 2019, Page 33-38  XML PDF (490.95 K)
Document Type: Original Article
DOI: 10.21608/rpbs.2019.12251.1032
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Authors
Hala Zaatout email orcid 1; Doaa Ghareeb2; Alshimaa Abd-Elgwad2; Amany Ismael3
1Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
2Biochemistry, Department of Biochemistry, Faculty of Science, Alexandria University, Egypt
3Oceanography Science, Faculty of Science, Alexandria University, Egypt
Abstract
Ulva lactuca is widespread green algae. In some regions, it is used in nutrition. Its nutrients include iron, protein, iodine, vitamins (A, B1, and C) and trace elements. Their extracts showed potential antibacterial, hypolipidemic, cardioprotective and chemoprotective activities. The main chemical constituents of Ulva lactuca methanolic crude extract and its fractions were investigated in this study using different phytochemical and chromatographic methods. Biologically guided fractionation of plants or seaweeds extracts is considered the first step in drug discovery. So, the algal crude extract was fractionated then in vitro bioscreened for the determination of diphenylpicrylhydrazyl (DPPH) antioxidant, (Nitric Oxide) NO radical scavenging and anti-inflammatory activities. Results showed that water fraction was the most active fraction. Phenolic content, detected from HPLC, play a role in the antioxidant activity. Finally, it can be concluded that Ulva water fraction is effective candidate to be used in the treatment of oxidative stress and related disorders
Keywords
green algae; Ulva lactuca; Phenolic; DPPH; Antioxidant activity
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