Accuracy of lung volumetry using three-dimensional computed tomographic (3D CT) imaging in chronic obstructive pulmonary disease patients | ||||
| Minia Journal of Medical Research | ||||
| Articles in Press, Accepted Manuscript, Available Online from 19 September 2023 | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjmr.2023.224450.1474 | ||||
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| Authors | ||||
Fatma Adel Abdel-Rahman  1; manal abu samra2; Nezar Refaat Tawfik3; Ahmed Mohamed Yassen4
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| 1radiodiagnosis department, faculty of medicine, Minya University | ||||
| 2Professor of diagnostic Radiology. Faculty of medicine, Minia University, Egypt | ||||
| 3Professor of Chest Disease and Tuberculosis, Faculty of medicine, Minia University, Egypt | ||||
| 4Radiology Department, Faculty of Medicine, Minia University, Minia, Egypt | ||||
| Abstract | ||||
| Background: Both developed and developing nations are affected by the disorder known as chronic obstructive pulmonary disease (COPD). The use of CT to offer phenotypic classification to assist in the clinical characterization of COPD patients is becoming more and more popular. The purpose of the current study was to examine if pulmonary function tests and quantitative computed tomography lung analyses were significantly correlated in people with chronic obstructive pulmonary disease. Methods: Pulmonary function tests and chest CT scans were performed on fifty COPD patients. For the quantitative evaluation, the low attenuation volume LAV-950 HU (%) of both lungs, the right lung, the left lung, and each lobe were obtained. The forced expiratory volume in 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (FEV1/FVC) were compared to the quantitative CT findings. Results: All quantitative assessment parameters with less than -950 HU showed a moderately negative correlation with pulmonary function tests (FEV1 and FEV1/FVC ratio), and LAV < -950 HU (%) values in both lungs, right lung, left lung, and each lobe were higher in patients with GOLD stages 3 and 4 of COPD compared to GOLD stages 1 and 2 (p 0.001). Conclusion: A further reliable, quick, and simple non-invasive method for determining the severity of emphysema is provided by the strong correlation between the parameters of pulmonary function tests and quantitative CT assessments of the disease. | ||||
| Keywords | ||||
| emphysema; quantitative CT; pulmonary function; COPD | ||||
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