Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals
Shahin, A., Fayed, S., El-Dien, N., Mohamed, N. (2023). Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals. EKB Journal Management System, (), -. doi: 10.21608/bmfj.2023.234610.1893
Ashraf Mohammed Shahin; Sahar Mohammed Fayed; Nehal Kamal El-Dien; Nashwa Farouk Mohamed. "Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals". EKB Journal Management System, , , 2023, -. doi: 10.21608/bmfj.2023.234610.1893
Shahin, A., Fayed, S., El-Dien, N., Mohamed, N. (2023). 'Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals', EKB Journal Management System, (), pp. -. doi: 10.21608/bmfj.2023.234610.1893
Shahin, A., Fayed, S., El-Dien, N., Mohamed, N. Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals. EKB Journal Management System, 2023; (): -. doi: 10.21608/bmfj.2023.234610.1893

Role of Vitamin - D Deficiency in Term Neonates with late-onset sepsis at Benha University Hospitals

Benha Medical Journal
Articles in Press, Accepted Manuscript, Available Online from 25 September 2023  XML PDF (318.44 K)
Document Type: Original Article
DOI: 10.21608/bmfj.2023.234610.1893
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Authors
Ashraf Mohammed Shahin1; Sahar Mohammed Fayed2; Nehal Kamal El-Dien email 3; Nashwa Farouk Mohamed4
1Professor of Pediatrics Faculty of Medicine – Benha University
2Professor of Clinical and Chemical Pathology Faculty of Medicine – Benha University
3Department of Pediatrics Faculty of Medicine – Benha University
4Lecturer of Pediatric Faculty of Medicine – Benha University
Abstract
Background: Neonatal In both full-term and premature newborns, sepsis is the leading cause of death and illness.Aim: The purpose of this research was to determine whether or not there is a correlation between vitamin-D status and LOS in full-term infants. Methods: Eighty participants were randomly assigned to one of two groups: Group I (LOS group) consisted of 40 newborns diagnosed with LOS at presentation between 72 and 28 days of age. Forty full-term, healthy newborns made comprised Group II, the control group. All of the newborns involved in the study had a thorough history taken, a comprehensive clinical examination performed, and several laboratory tests performed, including a complete blood count, C- reactive protein, Random blood sugar, blood culture, urine culture, and CSF analysis and culture. The 25-hydroxyvitamin D (25-OH-D) levels were measured quantitatively using an auto chemiluminescence immunoassay instrument (Maccura i1000). The results showed that the LOS group had significantly lower vitamin D levels than the control group, as well as a significantly greater prevalence of vitamin D insufficiency and severe deficiency. Patients with a maternal history of diabetes, hypertension, or recurrent urinary tract infections also had lower vitamin D levels than their rural counterparts.Conclusion Vitamin D levels were positively correlated with the APGAR score, while total bilirubin levels were inversely correlated with Vitamin D levels. .
Keywords
Vitamin-D; Deficiency; Term; Neonates; late-onset sepsis
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